Research Catalog
Alternatives to animal testing
- Title
- Alternatives to animal testing / editors, R.E. Hester and R.M. Harrison ; [contributors, Michael Balls and others].
- Publication
- Cambridge : Royal Society of Chemistry, [2006], ©2006.
- Supplementary Content
- Publisher description
Items in the Library & Off-site
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1 Item
| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
| Text | Request in advance | RA1199.4.A46 A48 2006 | Off-site |
Holdings
Details
- Additional Authors
- Description
- x, 123 pages : illustrations; 25 cm.
- Series Statement
- Issues in environmental science and technology, 1350-7583 ; 23
- Uniform Title
- Issues in environmental science and technology ; 23.
- Subjects
- Bibliography (note)
- Includes bibliographical references and index.
- Contents
- GENERAL OVERVIEW OF THE SAFETY EVALUATION OF CHEMICALS / Paul Illing -- Introduction -- Legislation and regulatory requirements -- The regulatory paradigm -- The interface between toxicology and risk assessment -- Interpreting toxicology -- Conclusions -- References -- INTERNATIONAL VALIDATION AND BARRIERS TO THE VALIDATION OF ALTERNATIVE TESTS / Michael Balls -- Introduction -- Background to the validation process -- The validation process -- Problems being encountered in implementing the validation process -- The need for an invalidation process -- Concluding remarks -- References -- IN VITRO TESTING FOR ENDOCRINE DISRUPTORS / Robert D. Combes -- Introduction -- In silico approaches -- In vitro tests for EDs -- Discussion -- Conclusions -- Acknowledgment -- References -- iNTELLIGENT APPROACHES TO SAFETY EVALUATION / Derek J. Knight -- Introduction -- Hazardous properties assessment -- Risk assessment -- Existing studies and literature data -- Surrogate data: calculation, read across and SAR/QSAR -- Alternatives to animal toxicology studies -- Data waivers -- Expert reports and weight of evidence -- Preliminary risk assessments -- EU Registration, Evaluation and Registration Scheme (REACH) -- Data for REACH -- Regulatory planning & liaison with the regulators -- Common themes -- Acknowledgments -- References -- ALTERNATIVE TESTS AND THE 7TH AMENDMENT TO THE COSMETICS DIRECTIVE / Carl Westmoreland -- Introduction -- Overview of current approaches to risk assessment for cosmetics -- 7th Amendment to the EU Cosmetics Directive (76/768/EEC) -- Status of alternative tests -- Endpoints where risk assessment for cosmetics can be achieved without using animal data -- Endpoints where risk assessment for cosmetics cannot currently be achieved without using animal data -- New approaches to risk assessment without animals -- Acknowledgments -- Abbreviations -- References.
- ISBN
- 0854042113
- 9780854042111
- LCCN
- 2006494634
- OCLC
- ocm70885520
- 70885520
- SCSB-5330935
- Owning Institutions
- Columbia University Libraries