Research Catalog

Dynamics of cancer : incidence, inheritance, and evolution

Title
Dynamics of cancer : incidence, inheritance, and evolution / Steven A. Frank.
Author
Frank, Steven A., 1957-
Publication
Princeton, N.J. : Princeton University Press, [2007], ©2007.

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TextRequest in advance RC268.5 .F63 2007Off-site
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Holdings

Details

Description
xi, 378 pages : illustrations; 25 cm.
Summary
"This is the only book that presents a full analysis of the age of cancer onset. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For cancer biologists, population geneticists, evolutionary biologists, and demographers interested in aging, this book provides new insight into disease progression, the inheritance of predisposition to disease, and the evolutionary processes that have shaped organismal design."--BOOK JACKET.
Series Statement
Princeton series in evolutionary biology
Uniform Title
Princeton series in evolutionary biology.
Subject
  • Carcinogenesis
  • Cancer > Age factors
  • Cancer > Genetic aspects
  • Cancer > Epidemiology
  • Neoplasms > etiology
  • Age of Onset
  • Gene Expression Regulation, Neoplastic
  • Genetic Predisposition to Disease
  • Mutagenesis
  • Stem Cells
Bibliography (note)
  • Includes bibliographical references (p. [335]-359) and indexes.
Contents
1. Introduction -- 2. Age of cancer incidence -- 3. Multistage progression -- 4. History of theories -- 5. Progression dynamics -- 6. Theory I -- 7. Theory II -- 8. Genetics of progression -- 9. Carcinogens -- 10. Aging -- 11. Inheritance -- 12. Stem cells : tissue renewal -- 13. Stem cells : population genetics -- 14. Cell lineage history -- 15. Conclusions -- App. Incidence.
ISBN
  • 9780691133652 (cloth : alk. paper)
  • 0691133654 (cloth : alk. paper)
  • 9780691133669 (pbk. : alk. paper)
  • 0691133662 (pbk. : alk. paper)
LCCN
2007007855
OCLC
  • ocm85498596
  • 85498596
  • SCSB-5353819
Owning Institutions
Columbia University Libraries