Research Catalog

Title

Geriatric bioscience : the link between aging and disease / David Hamerman ; foreword by Robert N. Butler.

Author

Hamerman, David.

Publication

Baltimore : Johns Hopkins University Press, 2007.

Supplementary Content

• Contributor biographical information
• Publisher description

Items in the Library & Off-site

Details

Description

xvi, 287 pages, 12 unnumbered pages of plates : illustrations (some color); 24 cm

Summary

"It is increasingly important for physicians who treat older persons, and for researchers on aging, to understand how molecular biology informs clinical expressions of aging and age related conditions such as osteoporosis, diabetes, osteoarthritis, frailty, cancer, and dementia. In Geriatric Bioscience, Dr. David Hamerman translates basic scientific concepts into percepts of clinical practice, explores the connections between disease and the science behind it, and addresses how mechanisms of inflammation, cytokine expression, and stress responses influence disease. He also examines how preventive gerontology in the practice of medicine could compress morbidity, and he discusses cutting edge treatment such as cyclo-oxygenases, bisphosphonates, statins, cytokine inhibitors, and hormone therapies."--BOOK JACKET.

Subject

• Geriatrics
• Aging > pathology
• Age Factors
• Disease Susceptibility > physiopathology

Bibliography (note)

• Includes bibliographical references (p. [227]-279) and index.

Contents

1. The Emergence and Future of Geriatrics -- 2. An Introduction to Concepts of Molecular Biology / E. Richard Stanley -- 3. Aging -- 1. Trends in the Aging of the Population -- 2. What Is Aging? Can We Distinguish between Aging and Disease? -- 3. Mechanisms of Aging -- 4. Longevity: Genetics of Extended Life Span or Risk for Adverse Events -- 4. Interrelations of Certain Aging-related Conditions -- 1. Cytokines, Inflammation, and Responses to Stress -- 2. Atherosclerosis: Risk Factors for Cardiovascular Disease -- 3. The Metabolic Syndrome and Type 2 Diabetes -- 4. Osteoporosis -- 5. Osteoarthritis -- 6. Frailty and Related Conditions: Anorexia, Sarcopenia, Exercise -- 7. Cancer -- 8. Alzheimer Disease / Peter Davies -- 5. Interactive Therapies Significant for an Aging Population -- 1. Cyclooxygenases -- 2. Statins -- 3. Bisphosphonates -- 4. Thiazolidinediones and Peroxisome Proliferator-activated Receptor [gamma] -- 5. Cytokine Inhibitors as a Landmark for Newer Anti-inflammatory Therapies -- 6. Hormonal Therapies -- 6. Preventive Gerontology -- 1. The Compression or Expansion of Morbidity? -- 2. Healthy Lifestyle Practices -- 3. "Successful Aging"

ISBN

• 9780801886928 (hardcover : alk. paper)
• 0801886929 (hardcover : alk. paper)

LCCN

2007013963

OCLC

• ocn123053428
• 123053428
• SCSB-5379674

Owning Institutions

Columbia University Libraries