Research Catalog

Title

The molecular and genetic basis of neurologic and psychiatric disease / editors, Roger N. Rosenberg [and others].

Publication

Philadelphia : Wolters Kluwer Health/Lippincott Williams & Wilkins, [2008], ©2008.

Supplementary Content

Publisher description

Items in the Library & Off-site

Holdings

Details

Additional Authors

Rosenberg, Roger N.

Description

xxi, 882 pages, 8 pages of plates : illustrations (some color); 29 cm

Subject

• Nervous system > Molecular aspects
• Nervous system > Genetic aspects
• Molecular neurobiology
• Neurogenetics
• Nervous System Diseases > genetics
• Genetic Diseases, Inborn
• Mental Disorders > genetics

Bibliography (note)

• Includes bibliographical references and index.

Contents

Sect. I. General Concepts and Mechanisms of Disease -- 1. Repeat Expansion Disorders: General Concepts and Mechanisms of Disease / Vicky L. Brandt and Huda Y. Zoghbi -- 2. Mendelian, Nonmendelian, and Multigenic Inheritance and Complex Traits / Kensuke Shiga, Ken Inoue and James R. Lupski -- 3. Selected Genetically Engineered Models Relevant to Human Neurodegenerative Disease / Donald L. Price, Lee J. Martin, Alena V. Savonenko, Tong Li, Fiona M. Laird and Philip C. Wong -- 4. Gene Mapping to Gene Targeting: Application of Mouse Genetics to Human Disease / Deborah E. Cabin and George A. Carlson -- 5. Genomics and the Human Genome Project / Robert L. Nussbaum -- 6. Gene Therapy for Central Nervous System Disorders / Pedro R. Lowenstein, Kurt M. Kroeger, Maria G. Castro and Theodore Friedmann -- 7. Emerging Ethical Issues in Neurology, Psychiatry, and the Neurosciences / Arthur L. Caplan and Martha J. Farah -- 8. Genotype-Phenotype Correlations / Thomas D. Bird and Gerard Schellenberg -- Sect. II. Neurologic Diseases -- 9. Down Syndrome / Charles J. Epstein -- 10. Triplet Repeats: Genetics, Clinical Features, and Pathogenesis / Vicky L. Brandt and Huda Y. Zoghbi -- 11. Prion Diseases / James A. Mastrianni -- 12. The Mitochondrial Genome / Eric A. Schon -- 13. Mitochondrial Disorders Due to Mutations in the Mitochondrial Genome / Salvatore DiMauro and Eduardo Bonilla -- 14. Mitochondrial Disorders Due to Mutations in the Nuclear Genome / Michio Hirano -- 15. Mitochondria in Neurodegenerative Disorders / Jennifer Q. Kwong, Giovanni Manfredi and M. Flint Beal -- 16. Peroxisomal Disorders / Hugo W. Moser and Gerald V. Raymond -- 17. Gaucher Disease / Roscoe O. Brady and Raphael Schiffmann -- 18. The Niemann-Pick Diseases / Edward H. Schuchman and Robert J. Desnick -- 19. The G[subscript M2] Gangliosidoses / Edwin H. Kolodny -- 20. Metachromatic Leukodystrophy and Multiple Sulfatase Deficiency: Sulfatide Lipidosis / Edwin H. Kolodny and Swati Sathe -- 21. Krabbe Disease: Globoid Cell Leukodystrophy / David A. Wenger -- 22. The Mucopolysaccharidoses and the Mucolipidoses / Reuben Matalon, Kimberlee Michals Matalon and Gita Bhatia -- 23. Disorders of Glycoprotein Degradation: Sialidosis, Fucosidosis, [alpha]-Mannosidosis, [beta]-Mannosidosis, and Aspartylglycosaminuria / William G. Johnson -- 24. [beta]-Galactosidase Deficiency: G[subscript M1] Gangliosidosis, Morquio B Disease, and Galactosialidosis / William G. Johnson -- 25. Farber Disease: Acid Ceramidase Deficiency and Farber Lipogranulomatosis / Hugo W. Moser -- 26. Wolman Disease / Rita Alam and Frank M. Yatsu -- 27. Lysosomal Membrane Disorders: LAMP-2 Deficiency / Ichizo Nishino -- 28. Fabry Disease: [alpha]-Galactosidase A Deficiency / Robert J. Desnick -- 29. Schindler Disease: Deficient [alpha]-N-Acetylgalactosaminidase Activity / Robert J. Desnick and Detlev Schindler -- 30. Alzheimer Disease / Dennis J. Selkoe -- 31. Frontotemporal Dementias / Felix Geser, Virginia M.-Y. Lee and John Q. Trojanowski -- 32. Genetics of Movement Disorders / Juliette M. Harris, Janice Fraser and Stanley Fahn -- 33. The Inherited Ataxias / Roger N. Rosenberg and Henry L. Paulson -- 34. Canavan Disease / Reuben Matalon, Kimberlee Michals Matalon and Gita Bhatia -- 35. The Hereditary Spastic Paraplegias / John K. Fink -- 36. Neuro-oncology: The Neurofibromatoses / Ray Bogitch and David H. Gutmann -- 37. The Genetic Epilepsies / Jeffrey R. Buchhalter and Marc A. Dichter -- 38. Multiple Sclerosis / Stephen L. Hauser and Jorge R. Oksenberg -- 39. Peripheral Neuropathies / Steven S. Scherer, Kleopas A. Kleopa and Merrill D. Benson -- 40. The Molecular and Genetic Basis of Spinal Muscular Atrophies / Ching H. Wang -- 41. Congenital Myasthenic Syndromes / Andrew G. Engel -- 42. Dystrophinopathies / Eric P. Hoffman -- 43. Limb-Girdle Muscular Dystrophies / Rita Barresi and Kevin P. Campbell -- 44. The Congenital Myopathies / Heinz Jungbluth, Caroline A. Sewry and Francesco Muntoni -- 45. The Distal Myopathies / Bjarne Udd and Robert C. Griggs -- 46. Hereditary Inclusion-Body Myopathies / Valerie Askanas and W. King Engel -- 47. The Myotonic Dystrophies / Richard T. Moxley III and Giovanni Meola -- 48. Facioscapulohumeral Dystrophy / Rabi Tawil -- 49. Ion Channel Disorders / Devon Ryan and Louis Ptacek -- 50. The Phakomatoses / Scott R. Plotkin and Catherine J. Chu-Shore -- 51. Lipoprotein Disorders / Mary J. Malloy and John P. Kane -- 52. Apolipoprotein E: Structure and Function in Lipid Metabolism and Neurobiology / Yadong Huang and Robert W. Mahley -- 53. Cerebrotendinous Xanthomatosis / Vladimir M. Berginer, Gerald Salen and Shailendra B. Patel -- 54. Disorders of Lipid Metabolism / Stefano Di Donato and Franco Taroni -- 55. Glycogen Storage Diseases / Salvatore DiMauro and Orhan Hasan Akman -- 56. Disorders of Galactose Metabolism / Louis J. Elsas II -- 57. Inborn Errors of Amino Acid Metabolism / William L. Nyhan and Richard H. Haas -- 58. Disorders of the Urea Cycle / Lewis J. Waber -- 59. Disorders of Glucose Transport / Darryl C. De Vivo, Dong Wang and Juan M. Pascual -- 60. Maple Syrup Urine Disease: Clinical and Biochemical Considerations / David T. Chuang, Rody R. Cox, R. Max Wynn and Jacinta L. Chuang -- 61. Congenital Disorders of N-Linked Glycosylation / Marc C. Patterson -- 62. Disorders of Glutathione Metabolism / Ellinor Ristoff and Agne Larsson -- 63. Disorders of Purine Metabolism / William L. Nyhan -- 64. The Porphyrias / D. Montgomery Bissell -- 65. Friedreich Ataxia / Massimo Pandolfo -- 66. Disorders of Copper Metabolism: Wilson Disease and Menkes Disease / John H. Menkes -- 67. Genetic and Dietary Influences on Life Span / Richard Mayeux -- 68. Vitamins: Cobalamin and Folate / David Watkins, Michael Shevell and David S. Rosenblatt -- 69. Disorders of Biotin Metabolism: Treatable Neurologic Syndromes / Barry Wolf -- Sect. III. Psychiatric Disease -- 70. Psychiatric Diseases: Challenges in Psychiatric Genetics / Maja Bucan and Edward S. Brodkin -- 71. Depression / Kerry J. Ressler and Charles B. Nemeroff -- 72. Bipolar Disorder / Berit Kerner, Victor I. Reus and Nelson B. Freimer -- 73. Schizophrenia / David W. Volk and David A. Lewis -- 74. Obsessive-Compulsive Disorder and Tourette Syndrome / Lawrence Scahill, Flora M. Vaccarino, Marcos T. Mercadante and Paul J. Lombroso -- 75. Genetic Bases of Addictive Behaviors / Scott D. Philibin, Kristine M. Wiren and John C. Crabbe -- 76. Autism / M. L. Cuccaro, D. Q. Ma and Margaret A. Pericak-Vance -- Sect. IV. A Neurologic Gene Map -- 77. A Neurologic Gene Map / Roger N. Rosenberg, Anita Harding, Antonio V. Delgado-Escueta and Susan T. Iannaccone.

ISBN

• 9780781769563
• 0781769566

LCCN

2007020775

OCLC

• ocn134990981
• 134990981
• SCSB-8881463

Owning Institutions

Columbia University Libraries