Research Catalog
Hepatotoxicity : from genomics to in vitro and in vivo models
- Title
- Hepatotoxicity : from genomics to in vitro and in vivo models / editor, Saura C. Sahu.
- Publication
- Chichester, England ; Hoboken, NJ : John Wiley & Sons, [2007], ©2007.
- Supplementary Content
- Publisher description
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| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
| Text | Request in advance | RC848.H48 H43 2007 | Off-site | |
Not available - Please for assistance. | Text | Use in library | Off-site |
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Details
- Additional Authors
- Sahu, Saura C.
- Description
- xvi, 682 pages : illustrations; 25 cm
- Subject
- Bibliography (note)
- Includes bibliographical references and index.
- Contents
- Current in vitro models to study drug-induced liver injury / Julio C. Davila ... [et al.] -- Utilization of an in vitro hepatotoxicity test in the early stage of drug discovery / Ikuo Horii ... [et al.] -- Use of hepatocytes for characterizing a candidate drug's metabolism and drug interaction potential / Srikanth C. Nallani, John M. Strong, and Shiew Mei Huang -- Human-based in vitro experimental systems for the evaluation of human drug safety / Albert P. Li -- Hepatocytes as a model for screening food-related hepatotoxins and studying mechanisms of their toxicity / Saura C. Sahu -- Some experimental models of liver damage / Pablo Muriel -- Application of short- and long-term hepatocyte cultures to predict toxicities / Gregor Tuschl ... [et al.] -- Biomarkers of mycotoxin exposure in liver toxicity / Angela J. Harris -- Mechanisms of toxic liver injury / Nora Anderson and Jurgen Borlak -- A role of cytochrome P450 in quinone-induced hepatotoxicity / Yasuhiro Ishihara and Norio Shimamoto -- A mechanistic view of troglitazone hepatotoxicity / Rawiwan Maniratanachote and Tsuyoshi Yokoi -- Role of the Kupffer cell in hepatotoxicity and hepatocarcinogenesis / James E. Klaunig ... [et al.] -- Sinusoidal cells in liver injury and repair / Carol C. Gardner and Debra L. Laskin -- Cytokines in liver diseases / Pablo Muriel -- Bile acids as modulators of apoptosis / Rui E. Castro ... [et al.] --
- Drug-induced intrahepatic cholestasis by interaction with the hepatic bile salt export pump (BSEP) / Christoph Funk ... [et al.] -- Application of toxicogenomics in predicting hepatotoxicity: potentials and challenges / Wen Lin ... [et al.] -- Genomic profiling of liver injury / Kevin Gerrish and David E. Malarkey -- Use of DNA arrays in understanding hepatic test systems / Angela J. Harris and Daniel A. Casciano -- Prediction of hepatotoxicity based on the toxicogenomics database / Tetsuro Urushidani -- Relationship between N-acetyltransferase-2 gene polymorphism and isoniazid-induced hepatotoxicity / Yasuo Shimazu, Kunio Dobashi, and Masatomo Mori -- Human and animal-based differences in hepatic xenobiotic metabolism and toxicity / Peter J. O'Brien, Katie Chan, and Raymond J. Poon -- Hepatotoxicity in oncology drug development / Wei Chen, Kenneth Hastings, and John K. Leighton -- The potent rat hepatocarcinogen methapyrilene: an hypothesis regarding its hepatotoxicology / Daniel A. Casciano -- Botanical supplements and hepatotoxicity / Shabana Khan, Ikhlas Khan, and Larry Walker -- Physiologically based pharmokinetic modeling and risk assessment of hepatotoxicants / Kannan Krishnan.
- ISBN
- 9780470057162 (pbk. : alk. paper)
- 0470057165 (pbk. : alk. paper)
- LCCN
- 2007038233
- OCLC
- ocn173182720
- 173182720
- SCSB-5389082
- Owning Institutions
- Columbia University Libraries