Research Catalog

Title

Red cell development / Edited by James J. Bieker.

Publication

San Diego : Academic Press, 2008.

Items in the Library & Off-site

Holdings

Details

Description

xv, 274 pages, 8 pages of plates : illustrations (some color); 24 cm.

Series Statement

Current topics in developmental biology ; v. 82

Uniform Title

Current topics in developmental biology ; v. 82.

Subjects

• Erythropoiesis > Molecular aspects
• Erythrocytes
• Developmental biology

Note

• p. 249-274 contains table of contents for vol. 47-81.

Bibliography (note)

• Includes bibliographical references and index.

Contents

1. Ontogeny of Erythropoiesis in the Mammalian Embryo / Kathleen McGrath and James Palis -- 1. Introduction -- 2. Primitive Erythropoiesis -- 3. "Definitive" Erythropoiesis in the Fetus -- 4. Developmental Origins of Erythropoiesis -- 5. Conclusions -- 2. The Erythroblastic Island / Deepa Manwani and James J. Bieker -- 1. Introduction -- 2. Composition and Sites of Formation of Erythroblastic Islands -- 3. Cell-Cell Adhesive Interactions Within Erythroblastic Islands -- 4. Erythroblastic Island Functions -- 5. Conclusion -- 3. Epigenetic Control of Complex Loci During Erythropoiesis / Ryan J. Wozniak and Emery H. Bresnick -- 1. Introduction -- 2. Utility of Analyzing Erythropoiesis to Dissect Epigenetic Mechanisms -- 3. Epigenetic Control of the [beta]-like Globin Genes During Erythropoiesis -- 4. Epigenetic Control of the Gataz Locus During Erythropoiesis -- 5. Principles of Epigenetic Control Emerging from Studies of Erythropoiesis -- 4. The Role of the Epigenetic Signal, DNA Methylation, in Gene Regulation During Erythroid Development / Gordon D. Ginder, Merlin N. Gnanapragasam and Omar Y. Mian -- 1. Introduction -- 2. DNA Methylation in Erythroid Cell Differentiation -- 3. The [beta]-Globin Locus: A Model for the Role of DNA Methylation in Developmental Gene Regulation -- 4. DNA Methylation of the Human [alpha]-Globin Locus -- 5. DNA Methylation of Other Erythroid-Specific Genes -- 6. Conclusions and Future Directions -- 5. Three-Dimensional Organization of Gene Expression in Erythroid Cells / Wouter de Laat, Petra Klous, Jurgen Kooren, Daan Noordermeer, Robert-Jan Palstra, Marieke Simonis, Erik Splinter and Frank Grosveld -- 1. Introduction: Three-Dimensional Studies in a Historical Context -- 2. Long-Range Gene Activation and Gene Competition: DNA-Folding Matters? -- 3. Novel Biochemical Approaches to Study DNA Topology: Insight into the Spatial Organization of the [beta]-Globin Locus -- 4. The Functional Significance of Long-Range Interactions Between Regulatory Sequences -- 5. Long-Range Contacts in Other Gene Loci -- 6. Gene Positioning in the Nucleus: Spatial Coordination of Functionally Related Genes? -- 7. Future Directions for Studies on Nuclear Architecture: 4C Technology -- 6. Iron Homeostasis and Erythropoiesis / Diedra M. Wrighting and Nancy C. Andrews -- 1. Introduction -- 2. Iron Metabolism and Homeostasis -- 3. Hepcidin -- 4. Hepcidin and Erythropoeisis -- 5. Conclusions -- 7. Effects of Nitric Oxide on Red Blood Cell Development and Phenotype / Vladan P. Cokic and Alan N. Schechter -- 1. Nitric Oxide -- 2. NO Influence on Cell Differentiation -- 3. NO Interaction with RBCs -- 4. Effects of NO on Hemoglobin Expression -- 5. Role of NO During Malaria Pathogenesis -- 6. Effects of Fetal Hemoglobin Inducers on NO-cGMP Pathway -- 7. Summary: NO and Erythropoiesis -- 8. Diamond Blackfan Anemia: A Disorder of Red Blood Cell Development / Steven R. Ellis and Jeffrey M. Lipton -- 1. Introduction -- 2. Pathophysiology and Genetics: DBA, a Disorder of Ribosome Biosynthesis -- 3. Other Diseases Linked to Defects in Ribosome Synthesis -- 4. Ribosome Dysfunction and Red Blood Cell Development -- 5. DBA Is a Cancer Predisposition Syndrome -- 6. Treatment and Outcomes -- 7. Summary.

ISBN

• 9780123743664 (hbk.)
• 0123743664 (hbk.)

OCLC

• ocn213331226
• 213331226
• SCSB-5395114

Owning Institutions

Columbia University Libraries