Research Catalog

Title

Meta-analysis of binary data using profile likelihood / Dankmar Böhning, Ronny Kuhnert, Sasivimol Rattanasiri.

Author

Böhning, Dankmar.

Publication

Boca Raton : CRC Press, [2008], ©2008.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Kuhnert, Ronny.
• Rattanasiri, Sasivimol.

Description

xv, 190 pages : illustrations; 25 cm.

Summary

"Meta-Analysis of Binary Data Using Profile Likelihood focuses on the analysis and modeling of a meta-analysis with individually pooled data (MAIPD). It presents a unifying approach to modeling a treatment effect in a meta-analysis of clinical trials with binary outcomes." "After illustrating the meta-analytic situation of an MAIPD with several examples, the authors Introduce the profile likelihood model and extend it to cope with unobserved heterogeneity. They describe elements of log-linear modeling, ways for finding the profile maximum likelihood estimator, and alternative approaches to the profile likelihood method. The authors also discuss how to model covariate information and unobserved heterogeneity simultaneously and use the profile likelihood method to estimate odds ratios. The final chapters look at quantifying heterogeneity in an MAIPD and show how meta-analysis can be applied to the surveillance of scrapie." "Containing new developments not available in the current literature, along with easy-to-follow inferences and algorithms, this book enables clinicians to efficiently analyze MAIPDs."--BOOK JACKET.

Series Statement

Chapman & Hall/CRC interdisciplinary statistics series

Uniform Title

Interdisciplinary statistics.

Subjects

• Social Sciences
• Data Interpretation, Statistical
• Medicine > Research > Evaluation
• Meta-Analysis as Topic
• Meta-analysis
• Social sciences > Statistical methods

Note

• "A Chapman & Hall book."

Bibliography (note)

• Includes bibliographical references (p. 175-182) and indexes.

Contents

1. Introduction -- 2. The basic model -- 3. Modeling unobserved heterogeneity -- 4. Modeling covariate information -- 5. Alternative approaches -- 6. Incorporating covariate information and unobserved hetero- geneity -- 7. Working with CAMAP -- 8. Estimation of odds ratio using the profile likelihood -- 9. Quantification of heterogeneity in a MAIPD -- 10. Scrapie in Europe: a multicountry surveillance study as a MAIPD.

ISBN

• 9781584886303 (alk. paper)
• 1584886307 (alk. paper)

LCCN

2007049869

OCLC

• ocn184924593
• 184924593
• SCSB-5409217

Owning Institutions

Columbia University Libraries