Research Catalog

Title

Drosophila : a toolbox for the study of neurodegenerative disease / edited by Amritpal Mudher, Tracey A. Newman.

Publication

New York : Taylor & Francis Group, 2008.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Mudher, Amritpal.
• Newman, Tracey.

Description

x, 220 pages : illustrations; 24 cm.

Summary

"This book provides an overview of the ways in which the fruit fly (Drosophila melanogaster) is being used as a model organism to unravel the pathogenic processes that underlie human neurodegenerative disease." "Each chapter is written by a respected scientist and aims to demonstrate how they and others in this field have established Drosophila models of specific human neurodegenerative or neurological disease and how they have used them to further our understanding of these diseases."--BOOK JACKET.

Series Statement

• Experimental biology reviews
• SEB experimental biology series ; v. 60

Uniform Title

• Symposia of the Society for Experimental Biology ; no. 60.
• Experimental biology reviews.

Subject

• Nervous system > Animal models
• Drosophila
• Neurodegenerative Diseases > physiopathology
• Disease Models, Animal
• Drosophila melanogaster

Bibliography (note)

• Includes bibliographical references and index.

Contents

1. Modelling neurodegenerative diseases in Drosophila / David Shepherd, Amritpal Mudher and Tracey A. Newman -- 2. Drosophila genetics for the analysis of neurobiological disease / K. G. Moffat -- 3. Using Drosophila models to unravel pathogenic mechanisms that underlie neurodegeneration in tauopathies / Amritpal Mudher, Tracey A. Newman, Francis Chee and David Shepherd -- 4. Modelling cell and isoform type specificity of tauopathies in Drosophila / Sofia Grammenoudi, Maria Anezaki, Stylianos Kosmidis and Efthimios M. C. Skoulakis -- 5. Using a Drosophila model of Alzheimer's disease / Damian C. Crowther, Richard Page, Thomas Rival, Dhianjali S. Chandraratna and David A. Lomas -- 6. Amyloid peptides and ion channel function in Drosophila models of Alzheimer's disease / Laurence A. Brown, Christopher J. Alee, Jacqueline F. Kidd and David B. Sattelle -- 7. Genetic models of Parkinson's disease: mechanisms and therapies / Alexander J. Whitworth and Leo J. Pallanck -- 8. Modelling lysosomal storage disease in Drosophila / Sean T. Sweeney -- 9. Drosophila melanogaster in the study of epilepsy / Nara I. Muraro and Richard A. Baines -- 10. Hereditary spastic paraplegia genes in Drosophila: dissecting their roles in axonal degeneration and intracellular traffic / Xinnan Wang and Cahir J. O'Kane -- 11. Triplet repeat diseases: the role of fly models in understanding disease mechanisms and designing possible therapies / Zdenek Berger.

ISBN

• 9780415411851 (alk. paper)
• 0415411858 (alk. paper)

LCCN

2007033211

OCLC

• ocn164803201
• 164803201
• SCSB-5421536

Owning Institutions

Columbia University Libraries