Research Catalog

Title

Beyond apoptosis : cellular outcomes of cancer therapy / edited by Igor B. Roninson, J. Martin Brown, Dale E. Bredesen.

Publication

New York : Informa Healthcare, [2008], ©2008.

Items in the Library & Off-site

Details

Additional Authors

• Roninson, Igor B.
• Brown, J. M. (J. Martin)
• Bredesen, Dale E.

Description

xi, 352 pages : illustrations; 24 cm +

Subject

• Cancer > Chemotherapy
• Apoptosis
• Neoplasms > drug therapy
• Antineoplastic Agents
• Apoptosis > drug effects
• Cellular Senescence > drug effects
• Mitosis > drug effects

Bibliography (note)

• Includes bibliographical references and index.

Contents

1. A Personal History of the Development of the Apoptosis Concept / John F. R. Kerr -- 2. What Do the Clinical Data Tell Us About the Role of Apoptosis in Sensitivity to Cancer Therapy? / George D. Wilson -- 3. Response of Solid Tumors to Cancer Therapy: How Relevant Is Apoptosis? / J. Martin Brown -- 4. Historical Studies of Various Forms of Cell Death / Richard A. Lockshin and Zahra Zakeri -- 5. Toward a Mechanistic Taxonomy for Programmed Cell Death Pathways / Dale E. Bredesen -- 6. Caspase-Independent Apoptotic Cell Death / Lotti Egger -- 7. Autophagic Cell Death in Mammalian Cells / David T. Madden -- 8. The Cellular Decision Between Apoptosis and Autophagy / Yongjun Fan, Erica Ullman and Wei-Xing Zong -- 9. Parthanatos: PARP- and AIF-Dependent Programmed Cell Death / Valina L. Dawson and Ted M. Dawson -- 10. Paraptosis / Sabina Sperandio and Ian de Belle -- 11. Cellular Senescence and Its Effects on Carcinogenesis / Judith Campisi -- 12. Tumor Suppressing Activities of Senescent Keratinocytes / Brian J. Nickoloff -- 13. Senescence Induced by Repression of Human Papillomavirus Oncogenes in Cervical Cancer Cells / Daniel DiMaio, Kimberly Johung, Edward C. Goodwin, Stacy M. Horner and Kristin E. Yates -- 14. Treatment-Induced Tumor Cell Senescence and Its Consequences / Igor B. Roninson and Eugenia V. Broude -- 15. Senescence Regulation in Cancer Therapy / Abdelhadi Rebbaa -- 16. Exploiting Drug-Induced Senescence in Transgenic Mouse Models / Mehtap Kilic and Clemens A. Schmitt -- 17. Therapy-Induced Cellular Senescence: Clinical Relevance, Implications, and Applications / Daniel Y. Wu, Hui Wang, Qin Wang, Peter C. Wu and Hubert J. Vesselle -- 18. Mitotic Catastrophe in Cancer Therapy / Eugenia V. Broude, Jadranka Loncarek, Ikuo Wada, Kelly Cole, Christine Hanko, Igor B. Roninson and Mari Swift -- 19. How Do Cells Die After Irradiation? Time-Lapse Studies of Cells in Culture / William C. Dewey -- 20. Modes of Cell Death by Anticancer Agents: The Crucial Importance of Dose / J. Martin Brown.

ISBN

• 9780849391927 (hardcover : alk. paper)
• 084939192X (hardcover : alk. paper)

LCCN

2008025103

OCLC

• ocn144565832
• 144565832
• SCSB-5437991

Owning Institutions

Columbia University Libraries