Research Catalog

Title

Multichain immune recognition receptor signaling : from spatiotemporal organization to human disease / edited by Alexander B. Sigalov.

Publication

New York, N.Y. : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, [2008], ©2008.

Items in the Library & Off-site

Holdings

Details

Additional Authors

Sigalov, Alexander B.

Description

xxvii, 357 pages : illustrations (some color); 26 cm.

Series Statement

Advances in experimental medicine and biology ; v. 640

Uniform Title

Advances in experimental medicine and biology ; v. 640.

Subject

• Immune recognition
• T cells > Receptors
• Killer cells
• Cellular signal transduction
• Cell receptors
• Receptors, Immunologic
• Models, Immunological
• Signal Transduction

Bibliography (note)

• Includes bibliographical references and index.

Contents

Sect. I. MIRRs: Structure and Physiological Function -- 1. T-Cell Receptor / Jose M. Rojo, Raquel Bello and Pilar Portoles -- 2. B-Cell Receptor / Randall J. Brezski and John G. Monroe -- 3. FC Receptors / Maree S. Powell and P. Mark Hogarth -- 4. Natural Killer Cell Receptors / Roberto Biassoni -- 5. Platelet Glycoprotein VI / Stephanie M. Jung and Masaaki Moroi -- Sect. II. MIRE Signaling: Possible Mechanisms and the Techniques to Study and Visualize -- 6. Clustering Models / Wolfgang W. A. Schamel and Michael Reth -- 7. Segregation Models / Elaine P. Dopfer, Mahima Swamy, Gabrielle M. Siegers, Eszter Molnar, Jianying Yang and Wolfgang W. A. Schamel -- 8. Kinetic Proofreading Model / Byron Goldstein, Daniel Coombs, James R. Faeder and William S. Hlavacek -- 9. Serial Triggering Model / Jacob Rachmilewitz -- 10. Conformational Model / Ruth M. Risueno, Angel R. Ortiz and Balbino Alarcon -- 11. Permissive Geometry Model / Susana Minguet and Wolfgang W. A. Schamel -- 12. Signaling Chain Homooligomerization (School) Model / Alexander B. Sigalov -- 13. Visualization of Cell-Cell Interaction Contacts - Synapses and Kinapses / Michael L. Dustin -- 14. Visualization of Protein Interactions in Living Cells / Tomasz Zal -- Sect. III. MIRR Signaling and Therapy of Immune Disorders -- 15. Immunogenicity in Peptide-Immunotherapy: From Self/Nonself to Similar/Dissimilar Sequences / Darja Kanduc -- 16. Therapeutic Application of Transmembrane T and Natural Killer Cell Receptor Peptides / Nicholas Manolios, Marina Ali, Michael Amon and Veronika Bender -- 17. FC Receptor Targeting in the Treatment of Allergy, Autoimmune Diseases and Cancer / Akira Nakamura, Tomohiro Kubo and Toshiyuki Takai -- 18. Therapeutic Blockade of T-Cell Antigen Receptor Signal Transduction and Costimulation in Autoimmune Disease / Joseph R. Podojil, Danielle M. Turley and Stephen D. Miller -- 19. MHC and MHC-Like Molecules: Structural Perspectives on the Design of Molecular Vaccines / Vasso Apostolopoulos, Eliada Lazoura and Minmin Yu -- 20. School Model and New Targeting Strategies / Alexander B. Sigalov -- 21. Immune Receptor Signaling, Aging and Autoimmunity / Anis Larbi, Tamas Fulop and Graham Pawelec -- 22. Viral Pathogenesis, Modulation of Immune Receptor Signaling and Treatment / Walter M. Kim and Alexander B. Sigalov.

ISBN

• 9780387097886
• 0387097880

LCCN

2008025647

OCLC

• ocn231787272
• 231787272
• SCSB-5446126

Owning Institutions

Columbia University Libraries