Research Catalog

Medicinal protein engineering

Title
Medicinal protein engineering / edited by Yury E. Khudyakov.
Publication
Boca Raton : CRC Press, [2009], ©2009.

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TextRequest in advance TP248.65.P76 M43 2009Off-site

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Details

Additional Authors
Khudyakov, Yury E.
Description
xvii, 563 pages, 4 unnumbered pages of plates : illustrations (some color); 26 cm
Summary
"Medicinal Protein Engineering sheds light on this largely unchartered field, covering major strategies for engineering of proteins with predetermined biological properties. It discusses computational approaches to protein design and experimental approaches to protein construction. This volume also explores the tight connection between protein and genetic engineering. It moves researchers beyond experimental protein construction and theoretical protein design to the medicinal applications of engineered proteins."--BOOK JACKET.
Subjects
Bibliography (note)
  • Includes bibliographical references and index.
Contents
Pt. I. Computational Approaches -- Ch. 1. Web Resources for Protein Analysis / Stephen A. Cammer and Michael Czar -- Ch. 2. Artificial Neural Networks for Therapeutic Protein Engineering / James Lara -- Ch. 3. Phylogenetics and Medicinal Protein Engineering / Michael Anthony Purdy -- Ch. 4. Clustering and Classification Approaches to Identifying Protein Properties / Lilia Milkova Ganova-Raeva and Zoya Emilova Dimitrova -- Ch. 5. Analysis of Coordinated Substitutions in Proteins / David Campo -- Pt. II. Protein Engineering Targets: Vaccine -- Ch. 6. Tuning the Immune Response to Our Advantage: Design of Vaccines with Tailored Functions / Till A. Rohn and Martin F. Bachmann -- Ch. 7. Modification of HIV-1 Envelope Glycoprotein to Enhance Immunogenicity / Michael Aidoo, Salvatore Butera and Dennis Ellenberger -- Ch. 8. Engineering Better Influenza Vaccines: Traditional and New Approaches / Peter M. Pushko, Rick A. Bright, Terrence M. Tumpey and Gale E. Smith -- Ch. 9. Construction of Novel Vaccines on the Basis of Virus-Like Particles: Hepatitis B Virus Proteins as Vaccine Carriers / Paul Pumpens, Rainer G. Ulrich, Kestutis Sasnauskas, Andris Kazaks, Velta Ose and Elmars Grens -- Ch. 10. Polyomavirus-Derived Virus-Like Particles / Rainer G. Ulrich, Alma Gedvilaite, Tatyana Voronkova, Andris Kazaks, Kestutis Sasnauskas and Reimar Johne -- Ch. 11. Papillomavirus-Derived Virus-Like Particles / Andris Kazaks and Tatyana Voronkova -- Ch. 12. Recombinant Vaccines Against Hepatitis Viruses / Jonny Yokosawa, Nestor O. Perez and Livia M. G. Rossi -- Pt. III. Protein Engineering Targets: Diagnostics and Therapy -- Ch. 13. Designer Diagnostic Reagents and Allergens / Anna Obriadina -- Ch. 14. Peptide-Based Diagnostic Assays / Maria J. Gomara and Isabel Haro -- Ch. 15. Recombinant Antibodies / Alla Likhacheva and Tatyana Ulanova -- Ch. 16. Protein Engineering for HIV Therapeutics / James M. Smith, Dennis Ellenberger and Salvatore Butera -- Ch. 17. Recombinant Enzymes with New and Improved Properties / Lilia M. Ganova-Raeva -- Pt. IV. Special Expression Systems -- Ch. 18. Production of Pharmaceutical Compounds in Plants / Miguel Angel Gomez Lim -- Ch. 19. Plant Virus Biotechnology Platforms for Expression of Medicinal Proteins / Andris Zeltins -- Ch. 20. Alphaviruses: Multiplicity of Vectors and Their Promising Application as Vaccines and Cancer Therapy Agents / Anna Zajakina, Baiba Niedre-Otomere, Ekaterina Alekseeva and Tatyana Kozlovska.
ISBN
  • 9780849373688 (hardback : alk. paper)
  • 0849373689 (hardback : alk. paper)
LCCN
  • 2008025423
  • 40016222926
OCLC
  • ocn231787246
  • 231787246
  • SCSB-5449008
Owning Institutions
Columbia University Libraries