Research Catalog

Pathway analysis for drug discovery : computational infrastructure and applications

Title
Pathway analysis for drug discovery : computational infrastructure and applications / edited by Anton Yuryev.
Publication
Hoboken, N.J. : John Wiley & Sons, [2008], ©2008.
Supplementary Content
Publisher description

Items in the Library & Off-site

Filter by

3 Items

StatusVol/DateFormatAccessCall NumberItem Location
TextRequest in advance RM301.25 .P374 2008Off-site
BookTextRequest in advance RM301.25 .P374 2008 BookOff-site
TextUse in library Off-site

Holdings

Details

Additional Authors
Yuryev, Anton.
Description
x, 303 pages, 16 unnumbered pages of plates : illustrations (some color); 25 cm +
Summary
"With chapters contributed by pioneers in the field, Pathway Analysis for Drug Discovery offers readers both important new research findings and state-of-the-science reviews. The book not only presents the latest developments in pathway analysis, it also explains how these developments can improve and accelerate drug discovery, highlighting new opportunities for drug development." "Researchers who turn to this book will discover a variety of leading-edge methods to improve both the effectiveness and efficiency of their drug discovery and design efforts and gain an understanding of the role of pathway analysis infrastructure in modern and future drug discovery."--BOOK JACKET.
Series Statement
Wiley series on technologies for the pharmaceutical industry
Uniform Title
Wiley series on technologies for the pharmaceutical industry.
Subject
  • Drug development > Data processing
  • DNA microarrays > Data processing
  • Computational biology
  • Drug Design
  • Computational Biology
  • Microarray Analysis > methods
Bibliography (note)
  • Includes bibliographical references and index.
Contents
1. Introduction to Pathway Analysis / Anton Yuryev -- 2. Software Infrastructure and Data Model for Pathway Analysis / Fedor Bokov and Anton Yuryev -- 3. Automatic Pathway Inference in Heterogeneous Biological Association Networks / Anton Yuryev, Andrey Kalinin and Nikolai Daraselia -- 4. Algorithmic Basis for Pathway Visualization / Sergey Simakov, Iaroslav Ispolatov, Sergei Maslov and Alexander Nikitin -- 5. Pathway Analysis of High-Throughput Experimental Data / Andrey Y. Sivachenko -- 6. Integrative Pathway Analysis of Disease Molecular Data / Andrej Bugrim, Zoltan Dezso, Yuri Nikolsky and Tatiana Nikolskaya -- 7. Whole-Genome Expression Profiling of Papillary Serous Ovarian Cancer: Activated Pathways, Potential Targets, and Noise / John Farley, Laurent L. Ozbun and Michael J. Birrer -- 8. Mammalian Proteome and Toxicant Network Analysis / Sean Ekins and Craig N. Giroux -- 9. Unraveling Mechanisms of Toxicity with the Power of Pathways: ToxWiz Tool as an Illustrative Example / Mark P. Kuhnel, Bojana Cosovic, Goran Medic, Robert B. Russell and Gordana Apic -- 10. Impact of Chemistry Information on Pathway Analysis / Sreenivas Devidas -- 11. Propagation of Concentration Perturbations in Equilibrium Protein Binding Networks / Sergei Maslov and Iaroslav Ispolatov -- 12. An Adaptive System Model of the Yeast Glucose Sensor System / Todor Vujasinovic and Andre Sinisa Zampera -- 13. Present and Future of Pathway Analysis in Drug Discovery / Anton Yuryev.
ISBN
  • 9780470107058 (cloth)
  • 0470107057 (cloth)
LCCN
  • 2008015107
  • 99933526545
OCLC
  • 221960968
  • ocn221960968
  • SCSB-5467173
Owning Institutions
Columbia University Libraries