Research Catalog

Title

Antiviral research : strategies in antiviral drug discovery / edited by Robert L. LaFemina.

Publication

Washington, DC : ASM Press, [2009], ©2009.

Items in the Library & Off-site

Details

Additional Authors

• LaFemina, Robert L.
• American Society for Microbiology.

Description

xiii, 373 pages, 24 unnumbered pages of plates : illustrations (some color); 29 cm

Subject

• Antiviral agents
• Antiviral Agents
• Drug Discovery
• Viral Proteins
• Virus Diseases > drug therapy

Bibliography (note)

• Includes bibliographical references and index.

Contents

1. Antiherpesviral DNA Polymerase Inhibitors / Donald M. Coen -- 2. Entry Inhibitors of Human Immunodeficiency Virus / Masanori Baba -- 3. Human Immunodeficiency Virus Type 1 Non-Nucleoside Reverse Transcriptase Inhibitors / Dirk Jochmans, Johan Vingerhoets, Eric Arnoult, Luc Geeraert and Jerome Guillemont -- 4. Nucleoside Analogue Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase / Jerome Deval and Matthias Gotte -- 5. Integrase as a Novel Target for the Inhibition of Human Immunodeficiency Virus Type 1 Infection: Current Status and Future Perspectives / Linos P. R. Vandekerckhove, Frauke Christ, Zeger Debyser, Andrew Owen, David Back, Arnout Voet, Jonathan Schapiro and Dirk Vogelaers -- 6. Human Immunodeficiency Virus Type 1 Tat and Rev as Potential Targets for Drug Development / Sergei Nekhai and Kuan-Teh Jeang -- 7. Inhibitors of the Human Immunodeficiency Virus Protease / Jorge L. Martinez-Cajas and Mark A. Wainberg -- 8. Hepatitis C Virus Polymerase as a Target for Antiviral Drug Intervention: Non-Nucleoside Inhibitors / Yaya Liu, Yupeng He and Akhteruzzaman Molla -- 9. Nucleoside Analog Inhibitors of Hepatitis C Viral Replication / Steven S. Carroll and Robert L. LaFemina -- 10. Antiviral Targets in Orthopoxviruses / Mark N. Prichard and Earl R. Kern -- 11. Influenza Virus Antiviral Targets / Gillian M. Air and Wayne J. Brouillette -- 12. Developments in the Search for Small-Molecule Inhibitors for Treatment of Severe Acute Respiratory Syndrome Coronavirus / Dale L. Barnard and Yohichi Kumaki -- 13. Antiviral Treatment of Flaviviruses / Justin G. Julander -- 14. Clinical Aspects of Hepatitis C Virus Infection / David Durantel and Fabien Zoulim -- 15. Microbicides: Molecular Strategies for Prevention of Sexually Transmitted Viral Disease / Raina N. Fichorova -- 16. Phenotypic Susceptibility Assays for Human Immunodeficiency Virus Type 1 / Neil T. Parkin, Eoin Coakley and Christos J. Petropoulos -- 17. Metabolism of Antiviral Nucleosides and Nucleotides / Adrian S. Ray and Michael J. M. Hitchcock -- 18. Targeting the Interferon Response for Antiviral Therapy / Michael D. Robek -- 19. Toll-Like Receptors: Novel Molecular Targets for Antiviral Immunotherapy / Raymund R. Razonable, Albert Eid and Martin Henault -- 20. New Herpes Simplex Virus Replication Targets / Sandra K. Weller -- Afterword: Closing Thoughts / Robert L. LaFemina, Richard Whitley, Marc S. Collett, Stephen Hughes and Joseph Colacino.

ISBN

• 9781555814397
• 1555814395

LCCN

2009008069

OCLC

• ocn311060139
• 311060139
• SCSB-5473993

Owning Institutions

Columbia University Libraries