Research Catalog

Title

Enzyme inhibition in drug discovery and development : the good and the bad / edited by Chuang Lu, Albert P. Li.

Publication

Hoboken, N.J. : Wiley, c2010.

Items in the Library & Off-site

Details

Additional Authors

• Lu, Chuang
• Li, A. P.

Description

xiii, 854 p., [8] p. of plates : ill. (some col.); 25 cm.

Summary

"Offering a unique approach that includes both the pharmacologic and pharmacokinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development." "Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery; discovery biologists and medical chemists will also broaden their understanding of DMPK."--BOOK JACKET.

Subjects

• Enzyme inhibitors
• Enzyme Inhibitors > pharmacology
• Enzyme Inhibitors > chemical synthesis
• Drugs > Metabolism
• Drug development
• Drug Discovery > methods

Bibliography (note)

• Includes bibliographical references and index.

Contents

Pt. I. Drug discovery approaches and technologies -- Pt. II. Inhibition of the drug metabolizing enzymes - the undesirable inhibition -- Pt. III. Inhibition of the drug target enzymes - the desirable inhibition.

ISBN

• 9780470281741 (cloth)
• 047028174X (cloth)

LCCN

2009014027

OCLC

• ocn318292649
• 318292649
• SCSB-8858563

Owning Institutions

Columbia University Libraries