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Cancer systems biology / edited by Edwin Wang.

Title
Cancer systems biology / edited by Edwin Wang.
Supplementary Content
Inhaltsverzeichnis

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TextRequest in advance RC267 .C375 2010Off-site

Details

Additional Authors
Wang, Edwin.
Description
xix, 419 p., [16] p. of plates : ill. (some col.); 26 cm.
Summary
"The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis, cancer researchers can uncover a series of new discoveries and biological insights." "Unique in its dualistic approach, Cancer Systems Biology discusses the recent progress in the understanding of cancer systems biology at a time when more and more researchers and pharmaceutical companies are looking into a systems biology approach to find drugs that can effectively be used to treat cancer patients." "Section I introduces basic concepts and theories of systems biology and their applications in cancer research, including case studies of current efforts in cancer systems biology. Section II discusses basic cancer biology and cuttingedge topics of cancer research for computational biologists. It contains an overview of genomics, cell signaling, and tumorigenesis, in addition to hot topics such as molecular mechanisms of cancer metastasis and the molecular relationships between solid tumors, their microenvironments, and tumor blood vessels. Rounding out the book's solid coverage, Section III explores a variety of computational tools and public data resources that are useful for studying cancer problems at a systems level." "Cancer system biology is still in its infancy as a field of study, but it is fast becoming indispensable in the battle to defeat cancer and develop successful new treatments. Cancer Systems Biology marks an important step toward reaching that goal."--BOOK JACKET.
Series Statement
Chapman & Hall/CRC mathematical and computational biology series ; [32]
Subject
  • Cancer > Research > Methodology
  • Gene Expression Regulation, Neoplastic > physiology
  • Gene Regulatory Networks > physiology
  • Genes, Neoplasm > physiology
  • Neoplasms > genetics
  • Systems Biology > methods
  • Systems biology
ISBN
  • 1439811857 (alk. paper)
  • 9781439811856 (alk. paper)
LCCN
2009039065
Owning Institutions
Columbia University Libraries