Research Catalog

NK cell mediated cytotoxicity : receptors, signaling, and mechanisms / editor, Eva Lotzová ; associate editor, Ronald B. Herberman.

Title
NK cell mediated cytotoxicity : receptors, signaling, and mechanisms / editor, Eva Lotzová ; associate editor, Ronald B. Herberman.
Publication
Boca Raton : CRC Press, c1992.

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StatusFormatAccessCall NumberItem Location
TextRequest in advance QW 568 N7375 1992Off-site

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Details

Additional Authors
  • Lotzová, Eva, 1936-
  • Herberman, Ronald B., 1940-
Description
474 p. : ill.; 27 cm.
Subject
  • Cancer > Immunological aspects
  • Killer cells
  • Cell-mediated cytotoxicity
  • Cancer cells
  • Cellular signal transduction
  • Cell receptors
  • Cell Adhesion Molecules
  • Cytotoxicity, Immunologic
  • Killer Cells, Natural > physiology
  • Receptors, Immunologic
  • Signal Transduction > physiology
Bibliography (note)
  • Includes bibliographical references and index.
Processing Action (note)
  • committed to retain
Contents
  • Molecular cloning of human and murine natural killer cell tumor recognition proteins -- Structure and function of the CD16:[beta]:[gamma] NK receptor complex -- Molecular characterization of a novel NK cell signal transduction molecule: NKR-P1 -- Modulation of function-associated molecules on natural killer cells alters recognition and cytotoxicity -- Bright phenotype of adhesion molecules on lymphocytes with high oncolytic function -- Human NK cell adhesion molecules (CAMS) -- Fibronectin receptors on NK cells -- Function of the fibronectin receptor on human NK cells -- Interaction of human natural killer cells with the vascular endothelium: characterization of their migratory ability and the adhesive molecules -- Signal transduction mechanisms in NK cell cytotoxicity.
  • (cont) Signal transduction during NK cell activation -- Shared structural and functional motifs for signal transduction in T lymphocytes and natural killer cells -- Characterization and functional significance of NKR-P1 (3.2.3. Antigen): a novel triggering molecule -- Role of IL-2 receptors in NK cell activation and proliferation -- Functional activities of Fc receptors on NK cells -- Leukocyte function antigen and CD16 adhesion and signaling in antibody-dependent NK cell mediated cytotoxicity -- Gene up-regulation in NK cell activation -- cDNA clones specific for NK and T cells -- Novel signalling molecules on rat NK cells -- TcR activation of CD8-mediated CTL binding to class I protein.
  • (cont) Characterization of a sulfatase from granules of natural killer (NK) cells -- Serine esterases in normal and interleukin-2 activated rat NK cells -- Cytotoxic activity of RBL cells transfected with the cytolysin/perforin gene -- Inhibition of T cell cytotoxicity with antisense perforin oligonucleotides -- Resistance of effector cells to perforin-mediated cytolysis -- Characterization of a membrane-associated cytotoxin on activated or leukemia natural killer cells -- Natural killer-resistance inducing factor (NK-RIF): a novel immunomodulatory cytokine -- A multifunctional perspective of the CD8 molecule -- Natural killer cell-B lymphocyte interactions: the role of target cell major histocompatibility class I molecules.
  • (cont) Triggers involved in NK cells and T lymphocytes oncolysis -- Subpopulations of human CD3⁻, CD16 NK cells identified by MoAb directed to triggering surface molecules: correlation with specific alloantigen recognition -- Mechanisms of lysis by murine cytolytic and helper T cell clones.
ISBN
0849362679 (acid-free paper)
LCCN
^^^91005199^
OCLC
  • 24671435
  • SCSB-14234391
Owning Institutions
Harvard Library