Research Catalog

Title

Lamarck's signature : how retrogenes are changing Darwin's natural selection paradigm / Edward J. Steele, Robyn A. Lindley, Robert V. Blanden.

Author

Steele, Edward John.

Publication

Reading, Mass. : Perseus Books, c1998.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Lindley, Robyn A.
• Blanden, Robert Vincent.

Description

xix, 286 p. : ill.; 22 cm.

Summary

"This controversial book challenges the accepted theories on the genetic mechanism of evolution. The story these three biologists have to tell may very well upset the whole field of biology.The traditional view of evolution?which grew out of the work of Gregor Mendel and Charles Darwin and is strongly supported by present-day scientists like Richard Dawkins and Stephen Jay Gould?assumes we are at the mercy of our genes, which we inherit largely unchanged from our parents, except for rare random mutations which accumulated and lead to change over evolutionary time. Those genes are coded in the chromosomes of the sperm and egg cells of the parents, and so only changes to those two types of cell have any chance of being passed down to the parents'? offspring. Any changes, accidents, or surgery to the rest of the parent?s bodies are not transmitted to the newborn.The theory of inheritance of acquired characteristics?if you build up your muscles your kids will be born with a propensity toward great strength?on the other hand, favored by Jean Lamarck in the nineteenth-century, was brought down by nineteenth-century science. But now, as this challenging and thrilling book shows, it looks as though, at least for certain structures in the body?s immune system, Lamarck may have been right after all.Based on their own ground-breaking work over the past two decades, as well as that of other molecular biologists, Steele, Lindley, and Blanden argue that for one adaptive body system there is strong molecular genetic evidence that aspects of acquired immunities developed by parents in their own lifetime can be passed on to their offspring. Certain to stimulate lively debate, Lamarck?s Signature gives new life and scientific credibility to the Lamarckian heresy?the notion of the inheritance of acquired characteristics." --Publisher description.

Series Statement

• Frontiers of science
• Helix books

Uniform Title

• Frontiers of science (Reading, Mass.)
• Helix book

Subject

• Lamarck, Jean Baptiste Pierre Antoine de Monet de, 1744-1829
• Darwin, Charles, 1809-1882
• RNA
• Evolutionary genetics
• Natural selection
• DNA
• Molecular Biology
• Evolution, Molecular
• Immunogenetics
• Antibody Diversity
• RNA

Note

• "Published in Australia by Allen & Unwin Pty Ltd"--T.p. verso.

Bibliography (note)

• Includes bibliographical references (p.262-271) and index.

Processing Action (note)

• committed to retain

Contents

The twin legacies of Lamarck and Darwin -- In the beginning there was RNA -- Why the immune system is so interesting -- The idea of 'clonal selection' -- Somatic mutation -- soma-to-gerline feedback -- Beyond the immune system?

ISBN

073820014X

LCCN

^^^98087900^

OCLC

40449772

Owning Institutions

Harvard Library