Research Catalog

Title

Mechanics of motor proteins and the cytoskeleton / Jonathon Howard.

Author

Howard, Jonathon, 1957-

Publication

Sunderland, Mass. : Sinauer Associates, Publishers, c2001.

Items in the Library & Off-site

Holdings

Details

Description

xvi, 367 p. : ill.; 25 cm.

Summary

This book is for biology, physics, and engineering students who want to learn about the principles of protein mechanics and how it applies to the morphology and motility of cells. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. Chapters are centered on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together. All concepts are introduced from first principles, and numerous boxed examples and figures aid the nonmathematical reader. For the mathematically inclined, detailed proofs of important results are included in the Appendix.

Subject

• Biomechanical Phenomena
• Cytoskeletal proteins
• Cytoskeletal Proteins
• Cell Movement
• Molecular Motor Proteins > physiology
• Cytoskeleton > physiology

Bibliography (note)

• Includes bibliographical references (p. [339]-360) and index.

Processing Action (note)

• committed to retain

Contents

Introduction -- Mechanical forces -- Mass, stiffness, and damping of proteins -- Thermal forces and diffusion -- Chemical forces -- Polymer mechanics -- Structures of cytoskeletal filaments -- Mechanics of the cytoskeleton -- Polymerization of cytoskeletal filaments -- Force generation by cytoskeletal filaments -- Active polymerization -- Structures of motor proteins -- Speeds of motors -- ATP hydrolysis -- Steps and forces -- Motility models: from crossbridges to motion.

ISBN

0878933344

LCCN

^^2001017017

OCLC

• 45743313
• SCSB-10218476

Owning Institutions

Harvard Library