Research Catalog

Starting with serotonin : how a high-rolling father of drug discovery repeatedly beat the odds / Ann G. Sjoerdsma.

Title
Starting with serotonin : how a high-rolling father of drug discovery repeatedly beat the odds / Ann G. Sjoerdsma.
Author
Sjoerdsma, Ann G.
Publication
Kitty Hawk, N.C. : Improbable Books, c2008.

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StatusFormatAccessCall NumberItem Location
Book/TextRequest in advance RM301.25 .S56 2008Off-site

Holdings

Details

Description
x, 617 p., [16] p. of plates : ill., ports.; 24 cm.
Subject
  • Sjoerdsma, Albert
  • Sjoerdsma, Albert, 1924-
  • 1900-1999
  • Drug Discovery > history
  • Pharmacology, Clinical
  • Research
  • Pharmacology > history
  • Drug Discovery > history
  • Pharmacologists > United States > Biography
  • Drugs > History > United States > 20th century
  • Drug development > United States > History > 20th century
  • History, 20th Century
  • Pharmaceutical Preparations > history
  • History, 20th Century > Biography
  • Pharmaceutical Preparations > history > Biography
  • United States
Genre/Form
  • Biography
  • Biographies.
Bibliography (note)
  • Includes bibliographical references (p. 485-580) and index.
Processing Action (note)
  • committed to retain
Contents
A maverick in the making -- Backdrop to the learning curve -- A wide range: hypertension, Serotonin, and Udenfriend -- The Carcinoid breakthrough and big-time stuff -- Going bananas -- The wild bunch "tools up" -- The journey to Aldomet -- Fishing in the collagen pool -- Tryptophan intoxication and the cheese reaction -- Eureka! The Carcinoid syndrome expands -- The Thalidomide shakeup -- Gangbusters and beating the odds -- The father and sons of clinical pharmacology -- The Demser® fix and Penicillamine -- Of patents and Parkinson's disease -- More explorations: SH rats, REM, and histaminase -- Goodbye, NIH ... bonjour, industry -- Zinc think and enzyme suicides -- The DFMO slam dunk -- Cincinnati defense and overhaul -- European clinical trials -- Cross-pollinating to Tryps and other parasites -- Hip, hip, hurray! The Seldane® breakthrough -- Troubleshooting Vigabatrin and Bendectin -- The resurrection drug -- A good time in the '80s -- The price of a two-bit merger -- Losing a blockbuster, saving a cure -- Appendix: biochemistry tracking sheet; A drug by all names.
ISBN
  • 9780615165585
  • 0615165583
LCCN
^^2007941455
OCLC
  • 191891314
  • SCSB-10081366
Owning Institutions
Harvard Library