Research Catalog

Title

Triumph of the heart : the story of statins / Jie Jack Li.

Author

Li, Jie Jack

Publication

Oxford ; New York : Oxford University Press, 2009.

Items in the Library & Off-site

Details

Description

xvii, 201 p. : ill.; 24 cm.

Summary

Over 25 million people in the U.S. alone have benefited from statins--such drugs as Lipitor, Zocor, Crestor, Pravachol, and other cholesterol-lowering medicines--in preventing stroke, heart attack, and other forms of coronary heart disease. But how didthese remarkable, life-saving drugs come into being? In "Triumph of the Heart", Dr. Jie Jack Li, a medicinal chemist and expert on drug discovery, tells for the first time the fascinating story of statins. Drawn from discussions with many scientists involved in the discovery and development of these drugs, the book illuminates the human side of science by revealing the role played by persistence, luck, and sudden insight that characterize major discoveries. For scientists in the drug industry, health care professionals, students of medicine, and all those intrigued by the basic human drive to explore and discover, 'Triumph of the Heart' offers a compelling view of one of the most important drug discoveries of our time.

Subject

• Geschichte 1950-2009
• Statins (Cardiovascular agents) > History
• Hydroxymethylglutaryl-CoA Reductase Inhibitors > history
• Coronary Disease > drug therapy
• Drug Design
• Drug Industry > history
• History, 20th Century
• History, 21st Century

Genre/Form

History

Bibliography (note)

• Includes bibliographical references (p. 175-188) and index.

Processing Action (note)

• committed to retain

Contents

Cholesterol -- Genesis of statins -- Merck's triumph -- Discovery of Lipitor -- Development of Lipitor -- To market, to market -- Baycol, Crestor, and drugs beyond statins -- Reflections.

ISBN

• 9780195323573 (cloth : alk. paper)
• 0195323572 (cloth : alk. paper)

LCCN

^^2008039597

OCLC

• 244416786
• SCSB-10158423

Owning Institutions

Harvard Library