Research Catalog
Untangling the double helix : DNA entanglement and the action of the DNA topoisomerases / James C. Wang.
- Title
- Untangling the double helix : DNA entanglement and the action of the DNA topoisomerases / James C. Wang.
- Author
- Wang, James C.
- Publication
- Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, c2009.
Items in the Library & Off-site
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1 Item
| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
| Text | Request in advance | QP616.D56 W36 2009 | Off-site |
Details
- Description
- xi, 233 p. : ill. (some col.); 24 cm.
- Subject
- Genre/Form
- Popular Work
- Popular works
- Bibliography (note)
- Includes bibliographical references and index.
- Processing Action (note)
- committed to retain
- Contents
- An insuperable problem -- Nature's solutions: the DNA topoisomerases -- Breaking a DNA strand and holding onto -- The broken ends -- A magic swivel -- Moving one DNA double helix through another -- Real-time viewing of the DNA topoisomerases in action -- Manifestations of DNA entanglement: replication and recombination -- Manifestations of DNA entanglement: gene expression -- Beyond DNA untanglement: new twists on an old theme -- From nature's battlefields to the clinical wards -- Appendix 1: identification of the covalent intermediates in topoisomerase-catalyzed reactions -- Appendix 2: catalysis of DNA breakage and rejoining by DNA topoisomerases.
- ISBN
- 9780879698638 (cloth : alk. paper)
- 0879698632 (cloth : alk. paper)
- 9780879698799 (pbk. : alk. paper)
- 0879698799 (pbk. : alk. paper)
- LCCN
- ^^2008054799
- OCLC
- 291908056
- SCSB-10058646
- Owning Institutions
- Harvard Library