Research Catalog

Title

Proceedings of the fourth Seattle Symposium in Biostatistics : clinical trials / Thomas R. Fleming, Bruce S. Weir, editors.

Author

Seattle Symposium in Biostatistics (4th : 2010 : Seattle, Wash.)

Publication

New York : Springer, c2013.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Fleming, Thomas R.
• Weir, B. S. (Bruce S.), 1943-

Description

viii, 249 p. : ill. (some col.); 23 cm.

Summary

This volume contains a selection of chapters based on papers presented at the Fourth Seattle Symposium on Biostatistics: Clinical Trials. These biostatistical symposiums, which unite leading researchers every five years, represent important developments in field. The Fourth Seattle Symposium was held in 2010 to celebrate the 40th anniversary of the University of Washington School of Public Health and Community Medicine. The Symposium featured keynote lectures by Robert O'Neill, Ross Prentice and Robert Temple, as well as invited talks by Jesse Berlin, Christy Chuang-Stein, David DeMets, Bill DuMouchel, Susan Ellenberg, Thomas Fleming, Laurence Freedman, Margaret Pepe, Steve Self, Richard Simon, Bruce Weir, John Whittaker and Janet Wittes. Invited panelists included Jesse Berlin, Bruce Binkowitz, Christy Chuang-Stein, Bill DuMouchel, Susan Ellenberg, Thomas Fleming, Henry Fuchs, Dominic Labriola, Robert O'Neill, Robert Temple and Janet Wittes. The thoroughly peer-reviewed papers and material from short courses that are showcased in this volume represent the theme of the symposium, clinical trials. These papers encompass recent methodological advances on several important topics, summaries of the state of the art of methodology in key areas of clinical trials, as well as innovative applications of the existing theory and methods. This volume will be a valuable reference for researchers and practitioners in the field of clinical trials.

Series Statement

Lecture notes in statistics-proceedings ; 1205

Uniform Title

Lecture notes in statistics (Springer-Verlag) v. 1205.

Subject

• Biometry
• Biometry > Congresses
• Biostatistics

Genre/Form

• Conference papers and proceedings
• Conference papers and proceedings.
• Congress

Note

• International conference proceedings.

Bibliography (note)

• Includes bibliographical references.

Processing Action (note)

• committed to retain

Contents

The role and potential of surrogate outcomes in clinical trials: have we made any progress in the past decade? -- On the use of biomarkers to eclucidate clinical trial results: examples from the women's health initiative -- On the use of biomarkers in vaccine research and development -- Recent developments in the use of clinical trials to support individualizing therapies: a regulatory perspective -- Oncology clinical trials in the genomic era -- using SNPs to characterize genetic effects in clinical trials -- Why is this subgroup different from all other subgroups? Thoughts on regional differences in randomized clinical trials -- Quantitative risk/benefit assessment: where are we? -- Identifying and addressing safety signals in clinical trials: some issues and challenges -- Past, present, and future of drug safety assessment -- Designing, monitoring, and analyzing group sequential clinical trials suing the RCTdesign package for R -- Genetic markers in clinical trials.

ISBN

• 9781461452447 (pbk. : alk. paper)
• 1461452449 (pbk. : alk. paper)
• 9781461452454 (ebk.)
• 1461452457 (ebk.)

LCCN

^^2012952276

OCLC

802321809

Owning Institutions

Harvard Library