Research Catalog

Title

Computational methods in synthetic biology / edited by Mario Andrea Marchisio.

Publication

New York : Humana : Springer, [2021].

Items in the Library & Off-site

Holdings

Details

Additional Authors

Marchisio, Mario Andrea,

Description

x, 255 pages : illustrations (black and white, and colour); 27 cm.

Summary

This second edition book provides complete coverage of the computational approaches currently used in Synthetic Biology. New chapters detail computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Computational Methods in Synthetic Biology, Second Edition aims to feature a broad overview of the research areas that can be met in the area of in silico Synthetic Biology.

Series Statement

Methods in molecular biology, 1940-6029 ; 2189

Uniform Title

Methods in molecular biology ; v.2189.

Subject

• Computational biology > Laboratory manuals
• Synthetic biology > Laboratory manuals

Bibliography (note)

• Includes bibliographical references and index (pages 251-255).

Source of Description (note)

• Description based on online resource; title from PDF title page (Springer, viewed January 11, 2021).

Contents

1. Using a Design of Experiments Approach to Inform the Design of Hybrid Synthetic Yeast Promoters -- Computational Design of Multiplex Oligonucleotide-Based Assays -- Computational Methods For The Design Of Recombinase Logic Circuits -- Modular Modeling Of Genetic Circuits in SBML Level 3.-- CRISPR-ERA: A Webserver for Guide RNA Design of Gene Editing and Regulation -- iGUIDE Method for CRISPR Off-target Detection -- Web-based Base Editing Toolkits: BE-Designer and BE-Analyzer -- Synthetic Gene Circuit Analysis and Optimization -- Monitoring Single S. cerevisiae Cells with Multi-Frequency Electrical Impedance Spectroscopy in an Electrode-integrated Microfluidic Device -- Construction of Protein Expression Network -- Systems-theoretic Approaches to Design Biological Networks with Desired Functionalities -- A Deterministic Compartmental Modeling Framework for Disease Transmission -- Computer Aided Assembly and Verification of Synthetic Chromosomes -- Minimal Genome Design Algorithms using Whole-Cell Models -- Tn-Core: Functionally Interpreting Transposon-Sequencing Data with Metabolic Network Analysis -- Genome-scale Metabolic Modeling of Escherichia coli and its Chassis Design for Synthetic Biology Applications -- A Systems Bioinformatics Approach to Interconnect Biological Pathways. .

ISBN

• 1071608215 (canceled/invalid)
• 9781071608210 (canceled/invalid)

Owning Institutions

Princeton University Library