Research Catalog

Molecular biology of cancer : mechanisms, targets, and therapeutics /

Title
Molecular biology of cancer : mechanisms, targets, and therapeutics / Lauren Pecorino, University of Greenwich.
Author
Pecorino, Lauren,
Publication
  • Oxford : Oxford University Press, [2012]
  • ©2012

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TextUse in library RC268.4 .P425 2012Off-site

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Details

Description
xviii, 342 pages : illustrations (some color); 25 cm
Summary
Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents.
Subject
  • Antineoplastic Agents > therapeutic use
  • Cancer > Molecular aspects
  • Cancer cells
  • Carcinogenese
  • Cell Transformation, Neoplastic > genetics
  • Cytostatikum
  • Krebs
  • Molecular Biology > methods
  • Molekularbiologie
  • Neoplasms > etiology
  • Neoplasms > genetics
  • Neoplasms > therapy
  • Tumorzelle
Bibliography (note)
  • Includes bibliographical references and index.
Contents
DNA structure and stability : mutations versus repair -- Regulation of gene expression -- Growth factor signaling and oncogenes -- The cell cycle -- Growth inhibition and tumor suppressor genes -- Apoptosis -- Stem cells and differentiation -- Metastasis -- The immune system, infections, and inflammation -- Nutrients, hormones, and gene interactions -- The cancer industry : drug development, pharmocogenomics, and clinical trial design -- Cancer in the future : focus on cancer vaccines and technology.
ISBN
  • 9780199577170
  • 019957717X
LCCN
2012932747
Owning Institutions
Princeton University Library