Research Catalog

Neuroprotective agents : clinical and experimental aspects

Title: Neuroprotective agents : clinical and experimental aspects / edited by Bruce Trembly and William Slikker, Jr.
Publication: New York : New York Academy of Sciences, 1995.

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Status	Format	Access	Call Number	Item Location
Request for On-site Use Request Scan How do I pick up this item and when will it be ready?	Book/Text	Use in library	RC347.5 .N487 1995	Off-site

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Additional Authors

Description

xi, 348 pages : illustrations; 24 cm.

Series Statement

Annals of the New York Academy of Sciences ; v. 765

Uniform Title

Annals of the New York Academy of Sciences ; v. 765.

Subject

Genre/Form

Congress
proceedings (reports)
Conference papers and proceedings
Conference papers and proceedings.
Actes de congrès.

Note

This volume contains the papers from a conference held in New York on July 31-August 3, 1994.

Bibliography (note)

Includes bibliographical references and indexes.

Additional Formats (note)

Also available in an electronic version.

Contents

Preface / Editors -- Clinical Potential for the Use of Neuroprotective Agents: a Brief Overview / Bruce Trembly -- Prophylactic Pharmacologic Neuroprotection against Focal Cerebral Ischemia / Saran Jonas -- Fetal Rat Model of Acute Perinatal Ischemia-Hypoxia / Zbigniew Binienda -- Evaluation of the Novel Neuroprotective Agent BW619C89 in the Middle Cerebral Artery Occlusion Model of Focal Ischemia in the Spontaneously Hypertensive Rat and Normotensive Fischer 344 Rat / Jeanette H. Swan and Michael J. Leach -- Quantitative Histological Evaluation of Neuroprotective Compounds / Andrew C. Scallet -- Brain Injury and Inflammation: a Putative Role of TNF[alpha] / Babak Arvin, Lewis F. Neville, Frank C. Barone and Giora Z. Feuerstein -- Comparison of Glutamine-Enhanced Glutamate Release from Slices and Primary Cultures of Rat Brain / John F. Bowyer, George W. Lipe, John C. Matthews, Andrew C. Scallet and David L. Davies -- Effect of Hypocapnia on Extracellular Glutamate and Glycine Concentrations during the Periischemic Period in Rabbit Hippocampus / Kyu Taek Choi, Jung Kil Chung, Chun Sik Kwak and Hae Kyu Kim -- Neuroprotective Effects of Free Radical Scavengers and Energy Repletion in Animal Models of Neurodegenerative Disease / Jorg B. Schulz and M. Flint Beal -- Neuroprotective Effects of Radical Scavengers in an Intact Dorsal Root Ganglion Hypoxia Model / P. R. Bar -- Short-Term Regulation of Neuronal Calcium Channels by Depolarization / Jai Liu, Aleta Rutledge and David J. Triggle -- Potential Interactions between Nimodipine and Adrenal Hormones / Robert L. Isaacson and Julie A. Varner -- Effects of Nimodipine on the EEG of Substance Abusers / Ronald I. Herning, Xiaoyan Guo and W. Robert Lange -- Nimodipine Improves Information Processing in Substance Abusers / Ronald I. Herning, Xiaoyan Guo and W. Robert Lange
Adenosine: a Prototherapeutic Concept in Neurodegeneration / Dag K. J. E. von Lubitz, Margaret F. Carter, Mark Beenhakker, Rick C.-S. Lin and Kenneth A. Jacobson -- Dexamethasone and the Prevention of Neonatal Hypoxic-Ischemic Brain Damage / Ursula I. Tuor -- Risk Assessment Strategies for Neuroprotective Agents / William Slikker, Jr. and David W. Gaylor -- Neuroprotective Use-Dependent Blockers of Na[superscript +] and Ca[superscript 2+] Channels Controlling Presynaptic Release of Glutamate / Stanley M. Goldin, Katragadda Subbarao, Rahul Sharma, Andrew G. Knapp, James B. Fischer, Deborah Daly, Graham J. Durant, N. Laxma Reddy, Lain-Yen Hu, Sharad Magar, Michael E. Perlman, Jun Chen, Steven H. Graham, W. F. Holt, David Berlove and Lee D. Margolin -- Receptor Subtypes Linked to Metabotropic Glutamate Receptor Agonist-Mediated Limbic Seizures in Mice / Joseph P. Tizzano, Kelly I. Griffey and Darryle D. Schoepp -- Neuroprotective Properties of the Uncompetitive NMDA Receptor Antagonist Remacemide Hydrochloride / Gene C. Palmer, Edward F. Cregan, Alfonso R. Borrelli and Frances Willett -- Safety, Tolerability and Pharmacokinetics of the N-Methyl-D-Aspartate Antagonist Ro-01-6794 706 in Patients with Acute Ischemic Stroke / Dextrorphan Study Group / Hoffmann-La Roche -- Rationale for Glutamate Antagonists in the Treatment of Traumatic Brain Injury / J. S. Myseros and R. Bullock -- Strategies for Neuroprotection with Glutamate Antagonists: Extrapolating from Evidence Taken from the First Stroke and Head Injury Studies / R. Bullock -- Clinical Pharmacology of CNS 1102 in Volunteers / Keith W. Muir, Donald G. Grosset and Kennedy R. Lees -- Evidence for Prolonged Release of Excitatory Amino Acids in Severe Human Head Trauma: Relationship to Clinical Events / R. Bullock, A. Zauner, J. S. Myseros, A. Marmarou, J. J. Woodward and H. F. Young
Neuroprotective Effect of Calcitonin Gene-Related Peptide following Subarachnoid Hemorrhage / B. Anthony Bell -- Small Animal Model of Focal Cerebral Ischemia for Studying Neuroprotective Agents / Jeremy P. Holland and B. Anthony Bell -- Quantitative Histological Evaluation of Neurotoxic Hippocampal Damage / Andrew C. Scallet -- Perinatal Brain Injury: Pathophysiology and Therapeutic Intervention / Chris Williams, Carina Mallard, William Tan, Barbara Johnston, Alistair Gunn, Kyla Marks and Peter Gluckman -- Role of the Growth Factor IGF-I and [actual symbol not reproducible] after Hypoxic-Ischemic Brain Injury / Chris Williams, Jian Guan, Odette Miller, Erica Beilharz, Heather McNeill, Ernest Sirimanne and Peter Gluckman -- Oxidative Brain Damage in Aged Mice: Protection by Caloric Reduction / Harbans Lal, Michael J. Forster and Raj S. Sohal -- ^
Sensitization and Desensitization of the NMDA Receptor Complex: Implications for Therapy / Linda H. Fossom and Phil Skolnick -- Initial Experience with Remacemide Hydrochloride in Patients with Acute Ischemic Stroke / Keith W. Muir and Kennedy R. Lees -- Tolerability, Pharmacokinetics and Pharmacodynamics of Increasing Intravenous Doses of 619C89, a Novel Compound for the Acute Treatment of Stroke, in Healthy Volunteers / A. J. Mercer, R. J. Lamb, Z. Hussein, S. Hobbiger and J. Posner -- N-Methyl-D-Aspartate Receptor Participation in Parkinson's Disease, a Neurodegenerative Disorder / Anita Verma and S. K. Kulkarni -- Randomized, Double-Blind, Placebo-Controlled Ascending Dose Tolerance Study of 619C89 in Acute Stroke / Keith W. Muir, Kennedy R. Lees, Steven J. C. Hamilton, Charles F. George, Stephen F. Hobbiger and Martin W. Lunnon -- Disposition and Pharmacokinetics of Remacemide Hydrochloride in Male Sprague-Dawley Rats / Stephen Curry, Dennis J. McCarthy, Ken R. Case, Mark S. Eisman, Matthew R. Marler and Nik A. Mahmood -- Cerebral Hemodynamic and Metabolic Effects of the Noncompetitive NMDA Antagonist CNS 1102 in Humans with Severe Head Injury / A. Wagstaff, G. M. Teasdale, G. Clifton and L. Stewart -- Effects of Nimodipine and Verapamil on Cerebral Blood Flow and Cerebrovascular Reactivity in Conscious Rabbits / Gustav B. Weinstein -- Clinical Pharmacology of CNS 1102 in Man / Keith W. Muir, Donald G. Grosset and Kennedy R. Lees -- Low Environmental Temperatures or Pharmacologic Agents That Produce Hypothermia Decrease Methamphetamine Neurotoxicity in Mice / S. F. Ali, G. D. Newport, R. R. Holson, W. Slikker, Jr. and J. F. Bowyer -- Biologically Based Dose-Response Model for Neurotoxicity Risk Assessment / William Slikker, Jr. and David W. Gaylor -- Role of Reactive Oxygen Species (ROS) in Neuronal Degeneration: Modulation by Protooncogene Expression / Anthony Verity, D. E. Bredesen and T. Sarafian
Phospholipase A[subscript 2] Regulation in Neural Function and Injury / M. Anthony Verity.

ISBN

0897669452
9780897669450
0897669460
9780897669467

LCCN

95021866

OCLC

ocm32699131
32699131
SCSB-2067914

Owning Institutions

Princeton University Library