Research Catalog

Molecular basis of drug action : proceedings of the International Symposium on Molecular Basis of Drug Action, held in Querétaro, Mexico, October 13-16, 1980

Title
Molecular basis of drug action : proceedings of the International Symposium on Molecular Basis of Drug Action, held in Querétaro, Mexico, October 13-16, 1980 / editors, Thomas P. Singer, Raúl N. Ondarza.
Author
International Symposium on Molecular Basis of Drug Action (1980 : Querétaro, Mexico)
Publication
New York, N.Y. : Elsevier/North Holland, ©1981.

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StatusFormatAccessCall NumberItem Location
TextUse in library RM300 .I55 1980Off-site

Details

Additional Authors
  • Singer, Thomas Peter, 1920-1999.
  • Ondarza, Raúl N.
Description
xix, 408 pages : illustrations; 25 cm.
Series Statement
Developments in biochemistry, 016-1714 ; v. 19
Uniform Title
Developments in biochemistry ; v. 19.
Subject
  • Molecular pharmacology > Congresses
  • Biopharmaceutics
  • Pharmacology > Congresses
  • Molecular biology > Congresses
  • Biopharmaceutics
  • Pharmaceutical Preparations > metabolism
  • Pharmacology
  • Molecular biology
  • Molecular pharmacology
Genre/Form
  • Congress
  • proceedings (reports)
  • Conference papers and proceedings
  • Conference papers and proceedings.
  • Actes de congrès.
Bibliography (note)
  • Includes bibliographies and index.
Contents
Drugs against microbial invaders: Mode of action penicillins and ³-cephalosporins: on the active centers of serine and Zn₊₊ D-alanyl-D-Ala peptidase / J.M. Ghuysen, J.-M. Frere, and M. Leyh-Bouille. Modern science and the design of drugs for infectious disease / S.S. Cohen. Biochemical and molecular strategies in chemotherapy of parasitic worm infections / T.E. Mansour. Mutasynthesis of antibiotics / K.L. Rinehart, Jr. -- Suicide inhibitors, the search for perfect drugs: Introduction / Usdin. Overview / T.P. Singer. Suicide inhibitors of GABA transaminase / B.W. Metcalf and A. Sjoerdsma. Enzyme-activated irreversible inhibitors of [alpha]-amino acid decarboxylases / M.J. Jung and J. Koch-Weser. Olefins as suicide inhibitors of cytochrome P-450 / P.R. Ortiz de Montellano, B.A. Mico, H.S. Beilan, and K.L. Kunze. Mechanism-based inactivators of pyridoxal phosphate enzymes / M. Johnston and C. Walsh. Can the suicide inactivation of MAO by deprenyl explain its pharmacological effects? / J. Knoll -- New directions in molecular pharmacology: Drug transport / D. Zakim. The design of thyroid drugs / E.C. Jorgensen. Angiotensin-converting enzyme inhibition: further explorations of an active-site model / M.A. Ondetti [and others]. A serontoninergic antihypertensive agent / E. Hong. Investigation of electrostatic structure of membranes: new approaches with spin labelling / David S. Cafiso, W. Hubbell. The dual action of opioids and opioid-specific neuronal kindling / J.E. Villarreal -- Ionic channels and pumps: New perspectives on the tetrodotoxin and saxitoxin receptors / C.Y. Kao. The sodium and potassium ion pump / R.L. Post. Structure and function of the voltage-dependent sodium channel / S.R. Levinson -- Mechanisms of drug resistance: Penam sulfone inhibition of the RTEM [beta]-lactamase / D.G. Brenner, J. Fisher, and C. Kemal. Gene amplification as a mechanism for drug resistance in cultured animal cells / C.C. Simonsen [and others]. The induction of cytochromes P-450 related to drug, steroid, and carcinogen metabolism / R.W. Estabrook [and others]. Aspects of enzyme-mediated aminoglycoside antibiotic resistance / M.J. Haas and J. Davies.
ISBN
  • 044400632X
  • 9780444006325
  • 0444006338
  • 9780444006332
LCCN
81003185
OCLC
  • ocm07552574
  • 7552574
  • SCSB-9132662
Owning Institutions
Princeton University Library