Research Catalog

Title

The winding road to discovering iPS cells : the life of Yamanaka Shinya / Yamanaka Shinya ; interviewer Midori Shinya ; translated by Tony Atkinson

Author

Yamanaka, Shin'ya

Publication

• Tokyo, Japan : Japan Publishing Industry Foundation for Culture (JPIC), 2021.
• ©2021

Items in the Library & Off-site

Details

Additional Authors

• Midori, Shin'ya, 1976-
• Atkinson, Tony, 1956-

Description

155 pages : illustrations, portraits; 22 cm.

Summary

The revolutionary discovery of induced pluripotent stem cells, or iPS cells, completely changed the world, particularly in the field of medical science. This groundbreaking achievement was made by Dr. Yamanaka Shinya of Kyoto University and won him the Nobel Prize for Physiology or Medicine in 2012. The road that led him to this accomplishment, however, was not an easy one; during his early days as a training orthopedic surgeon, Yamanaka was not skilled and was called "a hindrance" by his supervisor. He eventually changed course to become a researcher in the field of medical science and undertook postdoctoral studies in the United States, but he experienced a mild case of depression upon returning to Japan. Even when Yamanaka presented the results of his discovery of iPS cells, he could not immediately bask in the glory of his success, since many of his peers simply could not believe his achievement. In this volume, the Nobel Prize laureate talks openly about his life from his childhood days to his current daily life and discusses his views on the future of regenerative medicine. How were iPS cells developed and what can they do? Translated from a runaway bestseller in Japan and replete with a new preface for the English edition, this biography shows what science can do for mankind, and the possibilities that life holds. -- Back cover

Series Statement

Japan Library

Uniform Title

• Yamanaka Shin'ya sensei ni jinsei to aipīesu saibō ni tsuite kiite mita. English
• Japan library (Shuppan Bunka Sangyō Shinkō Zaidan)

Alternative Title

• Yamanaka Shin'ya sensei ni jinsei to aipīesu saibō ni tsuite kiite mita.
• Winding road to discovering induced pluripotent stem cells

Subject

• Yamanaka, Shin'ya > Interviews
• Yamanaka, Shin'ya
• Scientists > Japan > Biography
• Embryonic stem cells > Research
• Stem cells
• Scientists
• Japan

Genre/Form

• interviews.
• Biographies.
• Interviews.

Note

• First published in Japan in 2012 by Kodansha Ltd., Tokyo--Title page verso.
• Translated from the Japanese

Bibliography (note)

• Includes bibliographical references (pages 146-147) and index.

Contents

• Preface to the English edition / by Yamanaka Shinya -- Preface to the English edition / by Midori Shinya -- Introduction. -- Part 1. iPS cells : the path to their creation and their possibilities: Changing the way I run ; Aspiring to be a doctor ; More important than winning and losing ; Kobe University School of Medicine ; Jamanaka ; Diseases that defy the best medical treatment ; My first experiment ; Doctor Miura, something's seriously wrong! ; Hooked on research ; Scattershot job applications ; San Francisco ; VW and presentation skills ; Can male mice become pregnant? ; The first gene I discovered ; A homecoming tinged with regret ; Tom and Connie ; From research tool to research subject ; Post-American depression ; Two positive developments ; A battle for incoming graduate students ; My vision ; How to build Kyoto ; Cell blueprints ; Bookmarks in blueprints : transcription factors ; What is theoretically possible will happen ; A two-pronged strategy : long- and short-term goals ; Winnowing down candidates in the database ; Drilling down to 24 genes ; Onward to Kyoto University ; What a clever goy, eh? ; A shadow cast by the Fabrication Scandal ; They don't believe me! ; Perfect mouse iPs cells ; The race to develop human iPS cells ; The potential of regenerative medicine ; Understanding the causes of disease and discovering new drugs ; iPS cell stocks : a new kind of banking. --
• Part 2. Interview: Crouching down for takeoff ; Obstacles to publishing in leading journals ; A fine line for discovery of iPS cells ; Checking whether reprogramming has occured ; Bookmarks and black stickers ; iPS cells and ES cells are too much alike ; The Glis1 gene that functions in a fertilized egg ; Safety of iPS cells ; Commitment to an open laboratory ; Daily life ; Researchers can't work alone ; Proud to be a doctor. -- Afterword: The future of iPS cells -- References -- Index -- About the autor and interviewer -- Support the iPS Cell Research Fund.

ISBN

• 9784866581774
• 4866581778

LCCN

2020436519

OCLC

• on1247383935
• SCSB-14308383

Owning Institutions

Princeton University Library