Research Catalog

Treatment of Parkinsonism: the role of dopa decarboxylase inhibitors.

Title
Treatment of Parkinsonism: the role of dopa decarboxylase inhibitors. Edited by Melvin D. Yahr.
Publication
New York, Raven Press [1973]

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TextUse in library RC382.T7Off-site

Details

Additional Authors
  • Yahr, Melvin D. (Melvin David), 1917-2004
  • Parkinson's Disease Foundation (U.S.)
  • Merck Sharp & Dohme.
Description
xiv, 303 pages illustrations; 25 cm.
Series Statement
Advances in neurology, v. 2
Uniform Title
Advances in neurology ; v. 2.
Subject
  • Parkinson's disease > Congresses
  • Aromatic amino acid decarboxylases > Inhibitors > Therapeutic use > Congresses
  • Enzyme inhibitors > Congresses
  • Aromatic amino acid decarboxylases > Congresses
  • Dihydroxyphenylalanine > therapeutic use > congresses
  • Dihydroxyphenylalanine > pharmacology > congresses
  • Parkinson Disease > drug therapy > congresses
  • Aromatic amino acid decarboxylases
  • Aromatic amino acid decarboxylases > Inhibitors > Therapeutic use
  • Enzyme inhibitors
  • Parkinson's disease
  • Behandlung
  • Parkinsonismus
  • Parkinsonizm > leczenie
Genre/Form
  • Conference papers and proceedings
  • Konferenzschrift.
Note
  • "Contains the major presentations of a meeting held on November 28, 1972, under the joint sponsorship of the Parkinson's Disease Foundation and Merck Sharp & Dohme Research Laboratories."
Bibliography (note)
  • Bibliography: p. 279-296.
Contents
Mechanism of action of L-DOPA in Parkinsonism -- Enzymology and sites of action of monoamines in the central nervous system -- Inhibitors of aromatic amino acid decarboxylase, their biochemistry -- Localization of dopamine in brain following administration of L-DOPA and a decarboxylase inhibitor -- Cerebrospinal fluid levels of DOPA and 3-O-methyldopa in Parkinsonism during treatment with L-SOPA and MK-486 -- Experimental pharmacology of carbidopa (MI-486) and L-DOPA: animal studies -- Carbidopa in Parkinsonism: inhibition of the metabolism of L-[2-14C]-DOPA -- Modification by inhibition of decarboxylase of the cardiovascular effects of L-DOPA in animals -- Effects of carbidopa and L-DOPA on blood pressure in man -- Clinical studies of carbidopa and L-DOPA in the treatment of Parkinson's disease -- Treatment of Parkinson's disease with L-DOPA and Ro 4-4602: review and present status -- Catalytic role of pyridoxal phosphate and the regulatory involvement of pyridoxal kinase in the metabolism of monoamines -- Pyridoxine as an adjunct in the treatment of Parkinsonism -- Effect of pyridoxine on systemic L-DOPA metabolism -- DOPA effect: possible significance of transamination and tetrahydroisoquinoline formation -- Overview of present treatment of Parkinsonism with L-DOPA.
ISBN
  • 0911216472
  • 9780911216479
LCCN
73161964
OCLC
  • ocm00663208
  • 663208
  • SCSB-273754
Owning Institutions
Princeton University Library