Research Catalog

Molecular biology of the brain

Title
Molecular biology of the brain / edited by S.J. Higgins.
Publication
Princeton, N.J. : Princeton University Press, ©1999.

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StatusFormatAccessCall NumberItem Location
TextUse in library QP356.2 .M645 1999Off-site

Details

Additional Authors
Higgins, S. J. (Steve J.)
Description
xx, 196 pages : illustrations (some color); 25 cm.
Summary
  • The workings of the brain have long held a fascination for scientists. Yet, faced as they have been with the obvious anatomical & biochemical complexity of the brain, understanding its functions--more than superficially--has seemed an impossible goal. The authors of the essays in this volume, acknowledged experts in their specialties, have illustrated the power of molecular biology to dissect the molecular functioning of the brain. The volume has related essays on neurotransmitters & their receptors, aspects of neuronal development & neurodegeneration, the molecular biology of opiate action, & the concept of neuronal networks in the olfactory system. It continues with essays on some of the major healthcare problems that can be expected to yield to analysis by molecular genetical approaches--neurodegenerative & affective disorders such as schizophrenia, Alzheimer's disease, spongiform encephalopathies, prion diseases, & trinucleotide expansion disorders. The volume concludes first.
  • With an exciting account of how molecular biology is beginning to explain a phenomenon as complex as memory and, finally, a thought-provoking essay on future developments in the field.
Series Statement
Essays in biochemistry ; v. 33
Uniform Title
Essays in biochemistry ; v. 33.
Subject
  • Molecular neurobiology
  • Brain > Diseases > Molecular aspects
  • Neurobiology
  • Brain > physiology
  • Brain > physiopathology
  • Molecular Biology
  • Neurobiology
  • Molecular neurobiology
Bibliography (note)
  • Includes bibliographical references and index.
Contents
Molecular cues that guide the development of neural connectivity -- Understanding neurotransmitter receptors: molecular biology-based strategies -- Molecular analysis of neurotransmitter release -- Mitochondria in the life and death of neurons -- Neuro-regeneration: plasticity for repair and adaptation -- Molecular basis for opiate action -- Gases as neurotransmitters -- Molecular biology of olfactory receptors -- Pathology and drug action in schizophrenia: insights from molecular biology -- Genetics of Alzheimer's disease -- Use of brain grafts to study the pathogenesis of prion diseases -- Pathological mechanisms in Huntington's disease and other polyglutamine expansion diseases -- Matter of mind: molecular control of memory -- Future developments.
ISBN
  • 069100952X
  • 9780691009520
LCCN
00500868
OCLC
  • ocm43903964
  • 43903964
  • SCSB-14360500
Owning Institutions
Princeton University Library