Research Catalog

Title

DNA topoisomerases in cancer therapy : present and future / edited by Toshiwo Andoh.

Publication

New York : Kluwer Academic/Plenum Publishers, ©2003.

Items in the Library & Off-site

Details

Additional Authors

Andoh, Toshiwo.

Description

xii, 202 pages : illustrations (some color); 24 cm

Subject

• DNA topoisomerases > Inhibitors > Therapeutic use
• Cancer > Chemotherapy
• Topoisomerase Inhibitors
• Drug Delivery Systems
• Neoplasms > drug therapy
• DNS-Topoisomerasen
• Krebs Medizin

Bibliography (note)

• Includes bibliographical references and index.

Contents

Ch. 1 Reflections on an accidental discovery / James C. Wang -- Ch. 2 Mechanisms of topoisomerase I inhibition by anticancer drugs / Juana Barcelo / Takahisa Furuta / Yves Pommier / Haruyuki Takemura / Olivier Sordet -- Ch. 3 Mechanism of action of topoisomerase II-targeted anticancer drugs / Kenneth D. Bromberg / Neil Osheroff -- Ch. 4 Degradation of topoisomerase cleavable complexes / Leroy F. Liu -- Ch. 5 Yeast as a model system in the analysis of DNA topoisomerase I poisons / Herve R. Jacquiau / Mary-Ann Bjornsti -- Ch. 6 Understanding the action of drugs targeting TOP2: Yeast based systems for unraveling drug mechanisms / John L. Nitiss / Mobeen Malik -- Ch. 7 Cellular resistance to DNA topoisomerase I-targeting drugs / Toshiwo Andoh / Kae Yanase -- Ch. 8 Development of new topoisomerase I-targeting compounds as candidate anticancer drugs / Yves Pommier / ZhiYong Liao / LingHua Meng -- Ch. 9 Development of new topoisomerase II-targeting compounds as candidate anticancer drugs / Takao Yamori / Kae Yanase / Ken Umemura / Toshiwo Andoh.

ISBN

• 0306477440
• 9780306477447

LCCN

2003044717

OCLC

• ocm51892843
• 51892843
• SCSB-9731712

Owning Institutions

Princeton University Library