Research Catalog

Title

Neural degeneration and repair : gene expression profiling, proteomics, and systems biology / edited by Hans Werner Müller.

Publication

Weinheim ; Chichester : Wiley-VCH, ©2008.

Items in the Library & Off-site

Details

Additional Authors

Müller, Hans Werner, Prof. Dr.

Description

xv, 234 pages : illustrations; 25 cm

Summary

Focuses on the analysis of nerve cell damage and repair using genomics, transcriptomics, proteomics, glycomics and systems biology in order to develop novel therapeutic and diagnostic approaches for neural diseases. Following an introduction into the microarray technology in translational neuroscience, the book goes on to look at the use of '-omics' technologies to analyse molecular changes in traumatic injury, neuron degeneration and regeneration, oxidative stress response, neuropathic pain manifestation, and more. The work covers central nervous system as well as peripheral nervous system pathologies.

Subject

• Nervous system > Regeneration
• Nervous system > Diseases
• Nervous system > Degeneration
• Proteomics
• Nerve Degeneration
• Neurodegenerative Diseases > genetics
• Nerve Regeneration
• Gene Expression Profiling
• Proteomics
• Nervous System Diseases
• Nervous system > Degeneration
• Nervous system > Diseases
• Nervous system > Regeneration
• Nervendegeneration
• Molekulare Medizin
• Nervenregeneration

Bibliography (note)

• Includes bibliographical references and index.

Contents

Microarrays in systems neurobiology and translational neuroscience : from genome research to clinical applications / Jeremy A. Miller and Daniel H. Geschwind -- A meta-analysis of large-scale gene expression studies of the injured PNS : toward the genetic networks that govern successful regeneration / Floor J. Stam [and others] -- Analyzing complex gene expression profiles in sensorimotor cortex following spinal cord injury and regeneration promoting treatment / Fabian Kruse [and others] -- Unraveling plasticity of dorsal root ganglion and spinal cord neurons using cDNA arrays / Xu zhang, Hua-sheng Xiao, and Lan Bao -- The role of gene expression dependent molecular pathways in axon plasticity and neuron repair following acute CNS injury / Simone Di Giovanni -- Axonal mRNA in regeneration / Christina F. Vogelaar and James W. Fawcett -- Proteomic approaches to axon injury : postgenomic approaches to a posttranscriptional process / Izhak Michaelevski and Mike Fainzilber -- Genomics approaches to the study of neurodegeneration / Jeanine Jochems, Peter Buckley, and James Eberwine -- Redox proteomics and metabolic proteins in brain of subjects with Alzheimer's disease, mild cognitive impairment, and models thereof / Rukhsana Sultana, Tanea Reed, and D. Allan Butterfield -- Gene expression profiling of gliomas : improving the understanding of glioma biology and paving the way for molecular classification / Markus J. Riemenschneider and Guido Reifenbereger.

ISBN

• 9783527317073
• 3527317074

LCCN

99820616709

OCLC

• ocn213380102
• 213380102
• SCSB-9768335

Owning Institutions

Princeton University Library