Research Catalog

Title

Viral proteinases as targets for chemotherapy / edited by Hans-Georg Kräusslich, Stephen Oroszlan, Eckard Wimmer.

Publication

Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, ©1989.

Items in the Library & Off-site

Details

Additional Authors

• Kräusslich, Hans-Georg.
• Oroszlan, Stephen.
• Wimmer, Eckard.
• Cold Spring Harbor Laboratory.

Description

xv, 287 pages : illustrations (some color); 21 cm.

Series Statement

Current communications in molecular biology

Uniform Title

Current communications in molecular biology

Subject

• Viral proteinases > Inhibitors > Congresses
• Antiviral agents > Testing > Congresses
• Antiviral agents
• Chemotherapy
• Antiviral Agents
• Endopeptidases > genetics
• Endopeptidases > metabolism
• HIV > physiology
• Viral Proteins > metabolism
• Virus Replication > physiology
• Drug Therapy
• Antiviral agents > Testing
• Viral proteinases

Genre/Form

• Congress
• Conference papers and proceedings.
• Actes de congrès.

Note

• "A Banbury Center meeting."

Bibliography (note)

• Includes bibliographical references.

Contents

Proteolytic processing in viral replication / E. Wimmer -- Molecular genetics of picornavirus protein processing / M.A. Lawson ... [et al.] -- Proteolytic processing of the poliovirus polyprotein by 2A[superscript pro] / C.U.T. Hellen ... [et al.] -- Cleavage specificity of the EMC 3C proteinase / A.C. Palmenberg and G.D. Parks -- Processing of the cowpea mosaic virus polyproteins / J. Wellink ... [et al.] -- Molecular genetic analysis of a viral proteinase and its cleavage site: potential for posttranslational regulation of gene expression? / T.D. Parks ... [et al.] -- Viral branches of the trypsin-like proteinase family / J.F. Bazan -- Crystallographic analysis of cysteine-trypsin variants / R. Fletterick, M. Wilke, and M. McGrath -- Evidence for a second sindbis virus autoproteinase: in vitro processing of the virus nonstructural polyprotein. Addendum: inhibition of sindbis virus assembly by peptides that mimic the cytoplasmic domain of the virus glycoprotein / M.J. Schlesinger -- Structural and nonstructural proteinases of sindbis virus / J.H. Strauss ... [et al.] -- Adenovirus proteinase: properties of a recombinant enzyme expressed in E. coli / J.M. Weber and A. Houde -- Biosynthesis and proteolytic processing of retroviral proteins: an overview / S. Oroszlan -- Action of viral proteinase packaged in capsids of equine infectious anemia virus / M.M. Roberts and S. Oroszlan -- Retroviral proteinase as an aspartic proteinase / Y. Yoshinaka, I. Katoh, and Y. Ikawa -- Bacterial expression and activity of the Moloney murine leukemia virus proteinase / P. Calkins and R.B. Luftig -- Processing sequence of gag-pro polyprotein by HTLV-I proteinase / M. Hatanaka and S.H. Nam -- Expression and structure-function characterization of the HIV-1 proteinase / C. Debouck ... [et al.] -- Characterization of human immunodeficiency virus-1 proteinase / M.C. Graves ... [et al.] -- Activity and inhibition of the HIV proteinase / K. von der Helm ... [et al.] -- Processing of human immunodeficiency virus polyproteins by bacterially expressed HIV-1 proteinase / H.-G. Krausslich ... [et al.] -- Genetic analysis of the HIV-1 proteinase / R. Swanstorm ... [et al.] -- E. coli-expressed HIV-1 proteinase mutants containing Arg-87/Asn-88 substitutions are inactive / J.M. Louis ... [et al.] -- Crystallographic studies of AMV proteinase / M.E. Fraser ... [et al.] -- Structure of the aspartic proteinase from rous sarcoma retrovirus at 2 [angstrom] resolution / M. Jaskolski ... [et al.] -- Crystal structure of a retroviral proteinase from avian myeloblastosis associated virus / S.I. Foundling ... [et al.] -- Structural comparisons of retroviral and eukaryotic aspartic proteinases / J. Erickson ... [et al.] -- Inhibitor design from known structures / R.L. DesJarlais, G. Seibel, and I.D. Kuntz, Jr. -- Non-peptide inhibitors of HIV proteinases: synthetic analogs of cerulenin / J.J. Blumenstein ... [et al.] -- Expression of authentic and enzymatically active HIV-1 proteinase in bacteria and yeast / S. Pichuantes ... [et al.] -- Chemical synthesis approach to the molecular biology of retroviral proteinases: structure-function studies of the HIV-1 and HIV-2 enzymes and their substrates / S.B.H. Kent ... [et al.] -- Kinetic studies of synthetic cleavage site peptides by poliovirus 3C and HIV-1 and HIV-2 proteinases / B.M. Dunn ... [et al.] -- Structure-function analysis of the retroviral aspartic proteinase / J. Leis ... [et al.] -- Substrate specificity determinants of the HIV-1 proteinase / K. Partin ... [et al.] -- HIV-1 proteinase: substrates, inhibitors, and subunit interactions / P.L. Darke ... [et al.] -- Specificity and inhibition studies on MAV proteinase / P. Strop ... [et al.] -- Substrate specificity of poliovirus 3C and HIV proteinases / M. Skoog ... [et al.] -- Proteinase inhibitors as antiviral agents / B.D. Korant -- Targeted drug discovery for HIV infection / M.I. Johnston and J. McGowan.

ISBN

• 0879693355
• 9780879693350

LCCN

90101498

OCLC

• ocm21031538
• 21031538
• SCSB-1745409

Owning Institutions

Princeton University Library