Research Catalog

Title
  • Antibiotics : actions, origins, resistance / by Christopher Walsh.
Author
Walsh, Christopher.
Publication
Washington, D.C. : ASM Press, c2003.

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TextUse in library RM267 .W357 2003Off-site
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Details

Description
x, 335 p. : ill. (some col.); 26 cm.
Subject
  • Antibiotics
  • Drug resistance in microorganisms
Bibliography (note)
  • Includes bibliographical references (p. 297-328) and index.
Contents
Antibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics.
ISBN
  • 1555812546
  • 9781555812546
  • 9781555818937 (pbk.)
LCCN
2002152389
OCLC
  • ocm50859627
  • 50859627
Owning Institutions
Princeton University Library