Research Catalog

Medicinal chemistry approaches to personalized medicine

Title
Medicinal chemistry approaches to personalized medicine / edited by Karen Lackey and Bruce D. Roth.
Publication
Weinheim, Germany : Wiley-VCH, [2014]

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Details

Additional Authors
  • Lackey, Karen
  • Roth, Bruce D.
Description
xxvii, 377 pages : illustrations (some color); 25 cm.
Series Statement
Methods and principles in medicinal chemistry ; Volume 59
Uniform Title
Methods and principles in medicinal chemistry ; v. 59.
Subject
  • Drug development
  • Pharmaceutical chemistry
  • Patient-centered health care
  • Drugs > Design
  • Drug Design
  • Pharmacogenetics > methods
  • Precision Medicine > methods
  • Chemistry, Pharmaceutical
  • Patient-Centered Care
  • Drugs > Design
  • Drug development
  • Patient-centered health care
  • Pharmaceutical chemistry
  • Health and Wellbeing
Bibliography (note)
  • Includes bibliographical references and index.
Contents
1. Medicinal Chemistry Approaches to Creating Targeted Medicines -- 2. Discovery of Predictive Biomarkers for Anticancer Drugs -- 3. Crizotinib -- 4 Discovery and Development of Vemurafenib: First-in-Class Inhibitor of Mutant BRAF for the Treatment of Cancer -- 5. Targeting Basal-Cell Carcinoma: Discovery and Development of Vismodegib (GDC-0449), a First-in-Class Inhibitor of the Hedgehog Pathway -- 6. G-Quadruplexes as Therapeutic Targets in Cancer -- 7. Identifying Actionable Targets in Cancer Patients -- 8. DNA Damage Repair Pathways and Synthetic Lethality -- 9. DNA Damage Repair Pathways and Synthetic Lethality -- 10. From Human Genetics to Drug Candidates: An Industrial Perspective on LRRK2 Inhibition as a Treatment for Parkinson's Disease -- 11. Therapeutic Potential of Kinases in Asthma -- 12. Developing Targeted PET Tracers in the Era of Personalized Medicine -- 13. Medicinal Chemistry in the Context of the Human Genome.
ISBN
  • 9783527333943
  • 3527333940
  • 9783527677283 (canceled/invalid)
  • 9783527677276 (canceled/invalid)
  • 9783527677269 (canceled/invalid)
  • 9783527677252 (canceled/invalid)
OCLC
  • ocn868268627
  • 868268627
  • SCSB-9837281
Owning Institutions
Princeton University Library