Research Catalog

The Search for antiviral drugs : case histories from concept to clinic

Title
The Search for antiviral drugs : case histories from concept to clinic / Julian Adams, Vincent J. Merluzzi, editors.
Publication
Boston : Birkhäuser, ©1993.

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StatusFormatAccessCall NumberItem Location
TextUse in library RM411 .S39 1993Off-site

Details

Additional Authors
  • Adams, Julian, 1954-
  • Merluzzi, Vincent J., 1949-
Description
xii, 240 pages : illustrations; 24 cm
Subject
  • Antiviral agents
  • Nucleosides > Derivatives > Therapeutic use
  • HIV infections > Chemotherapy
  • Antiviral Agents
  • Nucleosides > therapeutic use
  • HIV Infections > drug therapy
  • Geschichte
  • HIV-Infektion
  • Virostatikum
  • Aufsatzsammlung
  • Virusziekten
  • Geneesmiddelen
  • Anti-inflamatorios (farmacologia)
Bibliography (note)
  • Includes bibliographical references and index.
Contents
  • Introduction : the first effective antiviral / Herbert E. Kaufman -- Discovery and development of zidovudine as the cornerstone of therapy to control human immunodeficiency virus infection / Kathryn H. Pattishall -- Discovery of nevirapine, a nonnucleoside inhibitor of HIV-1 reverse transcriptase / Julian Adams and Vincent J. Merluzzi -- Discovery of TIBO, a new family of HIV-1-specific reverse transcriptase inhibitors / Rudi Pauwels -- Discovery and development of 2-pyridinone HIV-1 reverse transcriptase inhibitors / Mark E. Goldman -- Discovery and development of the HIV proteinase inhibitor Ro 31-8959 / Noel A. Roberts and Sally Redshaw -- A new approach to antiviral chemotherapy : intervention in viral gene expression by HIV tat antagonists / Ming-Chu Hsu and Steve Tam -- Discovery of pirodavir, a broad-spectrum inhibitor of rhinoviruses / Koen Andries -- sICAM-1 as a receptor antagonist for rhinoviruses : a model system of adhesion molecules as cell receptors for viruses / Steven D. Marlin.
  • (Cont.) Inactivation of herpes simplex virus ribonucleotide reductase by subunit association inhibitors : a potential antiviral strategy / Michel Liuzzi and Robert Déziel.
ISBN
  • 0817636064
  • 9780817636067
  • 3764336064
  • 9783764336066
LCCN
93016405
OCLC
  • ocm27683878
  • 27683878
  • SCSB-2001711
Owning Institutions
Princeton University Library