Research Catalog
Mechanism of steroid hormone regulation of gene transcription
- Title
- Mechanism of steroid hormone regulation of gene transcription / Ming-Jer Tsai, Bert W. O'Malley.
- Author
- Tsai, Ming-Jer.
- Publication
- Austin, Tex. : R.G. Landes Co., 1994.
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1 Item
| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
| Text | Use in library | QP572.S7 T77 1994 | Off-site |
Details
- Additional Authors
- O'Malley, Bert W.
- Description
- 162 pages : illustrations; 26 cm.
- Series Statement
- Molecular biology intelligence unit
- Uniform Title
- Molecular biology intelligence unit (Unnumbered)
- Subject
- Steroid hormones > Receptors
- Genetic transcription > Regulation
- Cellular signal transduction
- Genetic transcription
- Receptors, Steroid > genetics
- Transcription, Genetic
- Signal Transduction
- Genetic transcription
- Cellular signal transduction
- Genetic transcription > Regulation
- Steroid hormones > Receptors
- Genregulation
- Signaltransduktion
- Steroidhormon
- Steroidhormonrezeptor
- Bibliography (note)
- Includes bibliographical references and index.
- Contents
- Nuclear hormone receptor superfamily / Aria Baniahmad, Thomas P. Burris, Ming-Jer Tsai -- Functional domains and modular structure of nuclear hormone receptors -- Diseases associated with mutations in nuclear hormone receptors -- Evolution of the nuclear hormone receptor superfamily -- Nuclear receptor: DNA interactions / Austin J. Cooney, Sophia Y. Tsai -- Historical perspective -- Hormone response elements -- Ligand dependence of DNA binding -- Physical structure of the nuclear receptor DNA-binding domain.
- Functional subdomains of the DNA-binding domain -- Ligand-binding domain dimerization function -- Mechanisms of target gene activation by steroid hormone receptors: insights from cell-free transcription systems / Milan Bagchi -- RNA polymerase II transcription machinery -- Components of a cell-free transcription system -- Reconstitution of steroid receptor-regulated gene transcription system -- Development of a steroid hormone-dependent cell-free transcription system -- Role of steroid receptors in the formation of preinitation complex for transcription.
- Interactions of receptors with the components of Pol II core transcription machinery -- Mechanism of ligand activation / George Allan -- Heat shock protein dissociation -- Nuclear translocation -- Dimerization and DNA binding -- Phosphorylation -- Conformational changes -- Hormones and anti-hormones -- Current model of steroid hormone action -- Receptor phosphorylation / Nancy L. Weigel -- Phosphorylation of steroid receptor family members -- Kinases and receptor phosphorylation -- Effect of phosphorylation on receptor functions.
- Effect of modulators of kinases and phosphatases on transcriptional activation of steroid receptor family members -- Orphan receptors: structure and function relationships / Orla M. Conneely, Bert W. O'Malley -- General structural features common to orphan and lignad-activated nuclear receptors -- Complexity of the nuclear receptor superfamily -- Structural requirements for interaction of orphan receptors with enhancer DNA elements -- Identification of target genes regulated by orphan receptors.
- Nuclear receptor activation pathways -- Ligand-independent activation of nuclear receptors -- Constitutive transactivation by nuclear receptors -- Nuclear receptors in development and differentiation / Beat Lutz [and others] -- Mechanisms of ecdysone action in drosophila development -- Retinoids in the axial organization of the vertebrate embryo -- Nuclear receptors in the developing nervous system.
- ISBN
- 1570590931
- 9781570590931
- LCCN
- 94019188
- OCLC
- ocm30510149
- 30510149
- SCSB-14408640
- Owning Institutions
- Princeton University Library