Research Catalog

The search for an AIDS vaccine : ethical issues in the development and testing of a preventive HIV vaccine

Title
The search for an AIDS vaccine : ethical issues in the development and testing of a preventive HIV vaccine / Christine Grady.
Author
Grady, Christine.
Publication
Bloomington : Indiana University Press, ©1995.

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Details

Description
193 pages; 24 cm.
Summary
  • Efforts to halt the spread of AIDS have failed so far, and the creation of a vaccine seems the best hope for controlling the disease. Yet the process of developing and testing an HIV vaccine raises a host of difficult ethical issues. These concerns are the focus of this timely and important book.
  • Describing the role of vaccines in controlling infectious disease, this study surveys the guidelines, regulations, and attitudes concerning human-subjects research. There is current information on the state of HIV research and the challenges facing scientists. Vaccine research differs considerably from drug research, and Grady explores the current wisdom governing research with human subjects. Proposing a model for the ethical conduct of vaccine research in general, this book applies it to the complex case of an HIV vaccine. Clinical trials are already ongoing, and the next step, field trials to determine efficacy, involves another set of issues - and a call for new strategies for ethical conduct. The Search for an AIDS Vaccine is essential reading for everyone interested in ethics and the conduct of HIV vaccine research.
Series Statement
Medical ethics series
Uniform Title
Medical ethics series.
Subject
  • National Commission for the Protection of Human Subjects
  • National Institutes of Health (U.S.)
  • United States. Food and Drug Administration
  • Belmont Report
  • Declaration of Helsinki
  • Nuremberg Code
  • AIDS (Disease) > Vaccination > Moral and ethical aspects
  • AIDS (Disease) > Prevention > Moral and ethical aspects
  • AIDS (Disease) > Research > Moral and ethical aspects
  • Clinical trials > Moral and ethical aspects
  • AIDS vaccines
  • Research
  • AIDS Vaccines
  • HIV Infections > prevention & control
  • Clinical Trials as Topic
  • Ethics, Medical
  • Research
  • research (function)
  • AIDS vaccines
  • AIDS (Disease) > Prevention > Moral and ethical aspects
  • AIDS (Disease) > Research > Moral and ethical aspects
  • Clinical trials > Moral and ethical aspects
  • Vaccins contre le SIDA
  • HIV, infections x Prévention et contrôle
  • Essais cliniques comme sujet
  • Éthique des médecins
  • Recherche
  • HIV-Infektion
  • Impfstoff
  • Klinische Prüfung
  • Ethik
  • Arzneimittelentwicklung
  • AIDS
  • Vaccins
  • Medische ethiek
  • AIDS (Disease) > Vaccination > Moral and ethical aspects
Bibliography (note)
  • Includes bibliographical references (p. [163]-185) and index.
Contents
1. Vaccines and Their Development: Historical, Social, and Scientific Perspectives -- 2. Human-Subjects Research and the Regulation of Drugs and Biologicals -- 3. Human-Subjects Research and HIV Vaccines -- 4. The State of HIV Vaccine Science -- 5. Planning Phase III HIV Vaccine Efficacy Trials -- 6. Summary.
ISBN
  • 0253326192
  • 9780253326195
LCCN
94035650
OCLC
  • ocm31242881
  • 31242881
  • SCSB-14652503
Owning Institutions
Princeton University Library